Would you FNA/biopsy ?

Sonopath Forum

Hi,

Patches is a 14 year old F/S Foxterrier which has “chronic”liver enzymes elevations for more then 16 months now. Liver enzymes ALKP and ALT are 1.5 to 2 X normal and this dog is on SAMe for the last year.She is doing good except one ‘seizure “like episode witnessed by owner.

My questions:

-Would you FNA/Biopsy the nodule/ rest of liver. This looks like one of the “reactive hepatopathy” described by EL in a previous post

Hi,

Patches is a 14 year old F/S Foxterrier which has “chronic”liver enzymes elevations for more then 16 months now. Liver enzymes ALKP and ALT are 1.5 to 2 X normal and this dog is on SAMe for the last year.She is doing good except one ‘seizure “like episode witnessed by owner.

My questions:

-Would you FNA/Biopsy the nodule/ rest of liver. This looks like one of the “reactive hepatopathy” described by EL in a previous post

-What do you say about the GB? Those hyperechoigenicities in the wall are related to mucosa/thick mucus? The majority of them are not shadowing so less likelly uroliths/sand. CBD was normal.

 

Thank you,

 

Calin

 

Comments

vetecho

lost the rest of images.

lost the rest of images.

vetecho

lost the rest of images.

lost the rest of images.

vetecho

this picture has the nodule.

this picture has the nodule. There are more then one

Thank you

vetecho

this picture has the nodule.

this picture has the nodule. There are more then one

Thank you

EL

This is likely a chronic

This is likely a chronic inflammatoy hepatopathy and any chronic condition that “lumps up” the liver like this merits a needle if empirical measures are not working. I push a needle on this as well preferably a bx because of the coarse architecture and that nodule to diff nod hyperplasia from chronic remodeling vs something more like an emerging lymphoma. FNA will help lean you to a direction but this is coarse enough to warrent core bx and maybe bile acids. The Gb is a bit echogenic and some minor debros but gioes along with chronic inflam hepatopathy.

So BA, coag panel, core bx of general parenchyma and the nodule if pssobile, lower 3rd intercostal approach and see what comes up. May need copper staining too but likely secondary if present in a 14 yr old rottie.

If its a money case and the pet is stable and BA are NOT up in a rottie at 14 with this liver??? big picture I wouldnt get too crazy on the diagnostics. Maybe a cursory fna to see what cell predominance comes up to play with our antigen surveilance theory:)

EL

This is likely a chronic

This is likely a chronic inflammatoy hepatopathy and any chronic condition that “lumps up” the liver like this merits a needle if empirical measures are not working. I push a needle on this as well preferably a bx because of the coarse architecture and that nodule to diff nod hyperplasia from chronic remodeling vs something more like an emerging lymphoma. FNA will help lean you to a direction but this is coarse enough to warrent core bx and maybe bile acids. The Gb is a bit echogenic and some minor debros but gioes along with chronic inflam hepatopathy.

So BA, coag panel, core bx of general parenchyma and the nodule if pssobile, lower 3rd intercostal approach and see what comes up. May need copper staining too but likely secondary if present in a 14 yr old rottie.

If its a money case and the pet is stable and BA are NOT up in a rottie at 14 with this liver??? big picture I wouldnt get too crazy on the diagnostics. Maybe a cursory fna to see what cell predominance comes up to play with our antigen surveilance theory:)

vetecho

Thank you Eric. Will start

Thank you Eric. Will start with a FNA. Bile acids were up but mild increase (37).Caudal pole of left adr was 0.83 cm. Don’t know haw big that is…? for a foxterrier.LDDex and ACTH both still negative for Cushings..

vetecho

Thank you Eric. Will start

Thank you Eric. Will start with a FNA. Bile acids were up but mild increase (37).Caudal pole of left adr was 0.83 cm. Don’t know haw big that is…? for a foxterrier.LDDex and ACTH both still negative for Cushings..

EL

Im sorry fox terrier not

Im sorry fox terrier not rottie. yes 0.8 is a bit big but often normal anomaly older dogs adenoma or hyperplasia but to watch

EL

Im sorry fox terrier not

Im sorry fox terrier not rottie. yes 0.8 is a bit big but often normal anomaly older dogs adenoma or hyperplasia but to watch

vetecho

will do US rechecks every 6

will do US rechecks every 6 months

Thank you

vetecho

will do US rechecks every 6

will do US rechecks every 6 months

Thank you

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