– 12 year old MN Labrador Retriever with unexplained weight loss despite fairly good appetite
– no vomiting or other GI signs
– bloodwork and urinalysis unremarkable with mild elevation in ALP
– chest rads unremarkable
– abdominal ultrasound showed a focal thickening in the fundus of the stomach – no other abnormalities found
– with this pet’s history of unexplained weight loss, I am concerned that this could be neoplasia carcinoma?lymphoma?
– I don’t think owners are going to biopsy What do you think of this lesion?
– 12 year old MN Labrador Retriever with unexplained weight loss despite fairly good appetite
– no vomiting or other GI signs
– bloodwork and urinalysis unremarkable with mild elevation in ALP
– chest rads unremarkable
– abdominal ultrasound showed a focal thickening in the fundus of the stomach – no other abnormalities found
– with this pet’s history of unexplained weight loss, I am concerned that this could be neoplasia carcinoma?lymphoma?
– I don’t think owners are going to biopsy What do you think of this lesion?
Comments
The gastric wall is thick
The gastric wall is thick but the detail loss is minimal. anythign else saying GI lsa ??/ epigastric ln? other GI lesions? I give beneift of doubt and put these guys on a helicobacter protocol and ensure not getting nsaids and recheck in about a wek if successful continue for 4 weeks . In the meantime do a cancer hunt elsewhere like the cns (check for subtle neuro signs), chest rads…maldigestion profile may be of help.
Here is my emprical “helocobacter protocol”… may use amoxy instead of zithro
Helicobacter/Gastritis protocol
A clinical trial of Zithromax (Dogs: 5-10 mg/kg p.o. q24h. May increase dosing interval to q48h after 3-5 days of treatment), Metronidazole (10-20 mg/kg po bid) , Pepcid ( 0.5-1 mg/kg sid) and Sucralfate (0.5-2 g/dog PO) or Omeprazole (1 mg/kg po sid) over the next 3 weeks along with a novel-protein or hydrolyzed diet with slurry feeding bid/tid. over the next 2-4 days and then increase to canned diet bid. Dry food should be avoided over the next 4 weeks. A recheck sonogram to assess GI improvement or progression would be ideal in 4 weeks.
The gastric wall is thick
The gastric wall is thick but the detail loss is minimal. anythign else saying GI lsa ??/ epigastric ln? other GI lesions? I give beneift of doubt and put these guys on a helicobacter protocol and ensure not getting nsaids and recheck in about a wek if successful continue for 4 weeks . In the meantime do a cancer hunt elsewhere like the cns (check for subtle neuro signs), chest rads…maldigestion profile may be of help.
Here is my emprical “helocobacter protocol”… may use amoxy instead of zithro
Helicobacter/Gastritis protocol
A clinical trial of Zithromax (Dogs: 5-10 mg/kg p.o. q24h. May increase dosing interval to q48h after 3-5 days of treatment), Metronidazole (10-20 mg/kg po bid) , Pepcid ( 0.5-1 mg/kg sid) and Sucralfate (0.5-2 g/dog PO) or Omeprazole (1 mg/kg po sid) over the next 3 weeks along with a novel-protein or hydrolyzed diet with slurry feeding bid/tid. over the next 2-4 days and then increase to canned diet bid. Dry food should be avoided over the next 4 weeks. A recheck sonogram to assess GI improvement or progression would be ideal in 4 weeks.