A 12-year-old MN Cairn Terrier dog with prior history of increased ALP activity (1 year ago) was presented for recent inappropriate urination in the house. Abnormalities on physical examination were severe dental tartar, tachypnea with an easily elicited cough, hepatomegaly, and bilateral nuclear sclerosis. The patient was treated with a course of antibiotics pending urinalysis. At recheck exam nine days later, the owner reported that the patient was polyuric/polydypsic, and his gums had been bleeding.

A 12-year-old MN Cairn Terrier dog with prior history of increased ALP activity (1 year ago) was presented for recent inappropriate urination in the house. Abnormalities on physical examination were severe dental tartar, tachypnea with an easily elicited cough, hepatomegaly, and bilateral nuclear sclerosis. The patient was treated with a course of antibiotics pending urinalysis. At recheck exam nine days later, the owner reported that the patient was polyuric/polydypsic, and his gums had been bleeding. Proteinuria, hematuria, and leukocyturia were present on urinalysis, but the specific gravity was normal. CBC showed lymphopenia and monocytosis; blood chemistry showed elevated ALP activity and mild hyperglycemia.