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Transitional Cell Carcinoma (TCC) in a 12 year old FS Chow dog

Case Study

Transitional Cell Carcinoma (TCC) in a 12 year old FS Chow dog

A 12-year-old FS Chow was presented for evaluation of persistent hematuria and stranguria. Urinalysis showed low-normal SG (1.020), hematuria, and leucosuria. Mildly elevated ALP activity was present on blood work.

A 12-year-old FS Chow was presented for evaluation of persistent hematuria and stranguria. Urinalysis showed low-normal SG (1.020), hematuria, and leucosuria. Mildly elevated ALP activity was present on blood work.

 

Sonographic Differential Diagnosis

Bladder mass.
Concurrent small bladder calculi.
Left lateral liver nodule.

Image Interpretation

The cystourethral junction and trigone in this patient revealed a 3 x 1.69 cm mineralizing mass obstructing the left ureter; it entered into the cystourethral junction. It is not resectable at this time; however would be amenable to ultrasound guided laser ablation at Ridgewood Veterinary Hospital, Ridgewood, NJ. Decompression of the ureter could be performed by laser ablation plus or minus ureteral stent placement.
Left liver presented a 1.35 cm mixed hyperechoic nodule that appears to be isolated. The remainder of the liver appeared unremarkable.

DX

TCC

Outcome

None

Comments

Fine needle aspirates recommended of the general liver as well as the liver nodule itself. No overt evidence of metastatic disease noted unless the left liver nodule represents a metastatic lesion; however this would be an odd pattern for transitional cell carcinoma for metastasis in my opinion.  

Clinical Differential Diagnosis

Bladder pathology– urolith, neoplasia, bacterial cystitis, polyploid cystitis;
Urethral pathology– lith, neoplasia, granulomatous urethritis

UA PH

6

UA PH

6

Sampling

None

UA Specific Gravity Range

1.020

Patient Information

Patient Name : Clarius N
Gender : Female, Spayed
Species : Canine
Type of Imaging : Ultrasound
Status : Complete
Liz Wuz Here : Yes
Code : 06_00210

Clinical Signs

  • Hematuria
  • Stranguria

Images

clarius_nestle_bladder_massclarius_nestle_left_ureter_obstructionclarius_nestle_kidney_left_pyelectasiaclarius_nestle_ub_stoneclarius_nestle_left_liver_nodule

Blood Chemistry

  • Alkaline Phosphatase (SAP), High

Clinical Signs

  • Hematuria
  • Stranguria

Urinalysi

  • Blood Present
  • WBCs Present