A 10-month-old intact male toy poodle dog was presented for evaluation of acute onset of vomiting. Initial lab work had shown azotemia (creatinine 3.3, BUN 95), which progressively increased over 3 days (creatinine 9, BUN 151). Severe proteinuria was present on urinalysis.
A 10-month-old intact male toy poodle dog was presented for evaluation of acute onset of vomiting. Initial lab work had shown azotemia (creatinine 3.3, BUN 95), which progressively increased over 3 days (creatinine 9, BUN 151). Severe proteinuria was present on urinalysis.
Case Study
Nephrosis with intratubular oxylates suggestive of antifreeze toxicity in a 10 month old MI miniature poodle
Sonographic Differential Diagnosis
Ethylene glycol toxicosis, other renal toxin, infectious disease (leptospirosis).
Image Interpretation
Both kidneys showed diffuse hyperechoic cortical changes and excessive cortex/medulla ratio.
DX
Nephrosis with intratubular oxylates, ethylene glycol toxicosis
Outcome
The patient was euthanized three days after presentation.
Clinical Differential Diagnosis
Acute renal failure – toxins (ethylene glycol), sepsis, trauma. Congenital renal disease with acute decompensation. Addison’s disease.
Sampling
Histopathology revealed moderate, acute, diffuse nephrosis with intratubular oxalates.
Video
Patient Information
Patient Name :
Jaffe B
Gender :
Male, Intact
Species :
Canine
Type of Imaging : Ultrasound
Status :
Complete
Liz Wuz Here :
Yes
Code :
06_00081
Clinical Signs
- Vomiting
Images
Blood Chemistry
- Azotemia
Clinical Signs
- Vomiting
Urinalysi
- Protein Present