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Lymphoma diagnosed by FNA in a 9 year old MN DSH cat

Case Study

Case Study

Lymphoma diagnosed by FNA in a 9 year old MN DSH cat

A 9-year-old MN DSH was presented for weight loss. The cat was febrile on physical exam (temperature of 105.0F). A blood chemistry profile revealed hyperbilirubinemia 4.1, hypermagnesemia 2.6 and elevated liver enzyme activities (elevated SAP, elevated ALT, and elevated AST).

A 9-year-old MN DSH was presented for weight loss. The cat was febrile on physical exam (temperature of 105.0F). A blood chemistry profile revealed hyperbilirubinemia 4.1, hypermagnesemia 2.6 and elevated liver enzyme activities (elevated SAP, elevated ALT, and elevated AST).

Sonographic Differential Diagnosis

Chronic inflammatory hepatopathy and mesenteric root lymphadenopathy. Cholangiohepatitis or lymphoma (due to lymphatic involvement) is suspected. Other neoplasia such as mast cell disease is less likely.

Image Interpretation

The liver is coarse with increased portal markings suggestive for chronic inflammatory hepatopathy and potential emerging lymphoma or similar neoplasia. Echogenic omentum is present associated with the caudal border of the liver capsule. This finding is suggestive for leakage of inflammatory mediators through the hepatic capsule. The spleen was uniformly enlarged. Mesenteric root lymph nodes are enlarged and encompass the ileocecal region.

DX

Lymphoma

Outcome

The patient was lost to follow up.

Clinical Differential Diagnosis

Cholangitis/cholangiohepatitis, hepatic neoplasia (lymphoma, carcinoma), pancreatitis, toxoplasmosis, FIP.

Sampling

Ultrasound-guided fine needle aspirates were obtained from the liver and spleen, both of which revealed lymphoma.

Patient Information

Patient Name : Max C
Gender : Male, Neutered
Species : Feline
Type of Imaging : Ultrasound
Status : Complete
Liz Wuz Here : Yes
Code : 08_00019

Clinical Signs

  • Weight loss

Exam Finding

  • Fever

Images

LiverSpleenLymphnodesatICCJ

Blood Chemistry

  • Alkaline Phosphatase (SAP), High
  • ALT (SGPT), High
  • AST (SGOT), High
  • Total Bilirubin, High

Clinical Signs

  • Weight loss