Left adrenal tumor in a 10 year old FS mixed breed dog

Case Study

Left adrenal tumor in a 10 year old FS mixed breed dog

A 10-year-old FS mixed breed dog was presented with a history of polyuria, polydypsia, and urinating in the house. Physical examination was non-remarkable. Urinalysis showed isosthenuria, 1+ proteinuria, 2+ hematuria, and struvite crystals. Abnormalities on CBC and blood chemistry were leukocytosis as a result of neutrophilia, monocytosis and basophilia, thrombocytosis, elevated AST, elevated ALT, and elevated GGT activity, and marked elevation of ALP activity. The patient had been treated with Amoxicillin.

A 10-year-old FS mixed breed dog was presented with a history of polyuria, polydypsia, and urinating in the house. Physical examination was non-remarkable. Urinalysis showed isosthenuria, 1+ proteinuria, 2+ hematuria, and struvite crystals. Abnormalities on CBC and blood chemistry were leukocytosis as a result of neutrophilia, monocytosis and basophilia, thrombocytosis, elevated AST, elevated ALT, and elevated GGT activity, and marked elevation of ALP activity. The patient had been treated with Amoxicillin.

Sonographic Differential Diagnosis

Right adrenal mass with invasive properties. The isosthenuria suggests that this mass is a functional adenocarcinoma, but a pheochromocytoma is also possible.

Image Interpretation

A mixed echogenic mass is noted deriving from the right adrenal gland and invading the phrenic vein and vena cava.

DX

Left adrenal tumor

Outcome

Urine culture and sensitivity, empirical therapy for the urinary tract infection, blood pressure measurements, and three view survey thoracic radiographs were recommended prior to any surgical or medical treatment of the left adrenal tumor. The owner, however, declined any further work-up. Several weeks later at a recheck appointment the right adrenal tumor was found to be increasing in size. The patient was treated with Naxcel (ceftiofur), Torbugesic, and Cephalexin. The patient was subsequently euthanized a few weeks later.

Comments

No video available on this patient.

Clinical Differential Diagnosis

Urinary tract infection, early renal disease, Cushing’s disease (iatrogenic, pituitary, or adrenal neoplasia). Liver disease – vacuolar hepatopathy, neoplasia, infectious.

Sampling

None taken.

Patient Information

Patient Name : Maggie A
Gender : Female, Spayed
Species : Canine
Type of Imaging : Ultrasound
Status : Complete
Liz Wuz Here : Yes
Code : 07_00042

Clinical Signs

  • Inappropriate Urination
  • PU-PD

Images

AlfanoLeAdrTumor

Blood Chemistry

  • ALT (SGPT), High
  • AST (SGOT), High
  • GGT High

CBC

  • Basophils, High
  • Monocytes, High
  • Neutrophils, High
  • Platelet Count, High
  • WBC, High

Clinical Signs

  • Inappropriate Urination
  • PU-PD

Urinalysi

  • Blood Present
  • Isosthenuria Present
  • Protein Present
  • Struvite crystals
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