Case Study

CYT – Multiple myeloma diagnosed by splenic FNA in a 6 year old FS DSH cat

The patient is a 6 year old FS DSH feline. Clinical exam findings were nonspecific, including dehydration, weight loss, and diarrhea. Altered CBC/Chem/UA values include neutrophilia, lymphopenia, elevated amylase, elevated BUN, hyperproteinemia, and marked hyperglobulinemia. FeCOV/Felv/FIV tests were negative.

The patient is a 6 year old FS DSH feline. Clinical exam findings were nonspecific, including dehydration, weight loss, and diarrhea. Altered CBC/Chem/UA values include neutrophilia, lymphopenia, elevated amylase, elevated BUN, hyperproteinemia, and marked hyperglobulinemia. FeCOV/Felv/FIV tests were negative.

Sonographic Differential Diagnosis

Suggestive for infiltrative splenic, mesenteric root, and intestinal disease. This is strongly suggestive for multiple myeloma, lymphoma or similar neoplasia. There is a minor potential for infectious disease.

Image Interpretation

The spleen was enlarged and micronodular with slight scalloping contour. The spleen measured 1.33 cm. The mesenteric root lymph nodes were enlarged at 0.62 cm with reactive surrounding fat. Other mesenteric root lymph nodes measured 1.4 x 2.0 cm with reactive fat. Slight free fluid was noted owing to lymphatic strangulation. The remainder of the bowel revealed increased muscularis to mucosa thickening with a 2:1 ratio.