04_00368 Mushu Z PLE

Case Study

04_00368 Mushu Z PLE

A 3-year-old NM Yorkie was presented for evaluation of appetite, vomiting, and diarrhea. Hypoalbuminemia was present on laboratory testing.

A 3-year-old NM Yorkie was presented for evaluation of appetite, vomiting, and diarrhea. Hypoalbuminemia was present on laboratory testing.

Sonographic Differential Diagnosis

Protein losing enteropathy.
Lymphangectasia type presentation with secondary ascites.
If the ascites is transudate based on abdominocentesis this would be most consistent with protein losing enteropathy and secondary albumin loss, but given that the bloodwork was taken 4 days prior to the sonogram my concern is that the albumin is likely lower than 1.7 at this point. Anything less than 1.5 would justify poor oncotic pressure and free fluid formation. Urinalysis and assessment for concurrent protein losing nephropathy would be recommended. Liver function may also be compromised adding to the albumin loss issue. Plasma transfusion, broad spectrum deworming, calcium supplementation, Purina HA or Royal Canin HP diet, Metronidazole and Prednisone therapy would all be indicated. However, corn oil testing and endoscopy would be ideal for a definitive diagnosis as well as mucosal, gastric and duodenal biopsies.

Image Interpretation

The gastrointestinal tract presented, diffusely thickened mucosa with mucosal striations. This is consistent with protein losing enteropathy and likely lymphangectasia. Anechoic free fluid is noted in moderate quantity.

DX

Suspect PLE

Outcome

The patient was euthanized.

Clinical Differential Diagnosis

Protein-losing nephropathy – IBD, lymphangectasia, neoplasia, foreign body, ulceration, dietary hypersensitivity

Sampling

None

Patient Information

Gender : Male, Neutered
Species : Canine
Type of Imaging : Ultrasound
Status : Complete

Clinical Signs

  • Diarrhea
  • Vomiting

Images

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Blood Chemistry

  • Albumin, Low

Clinical Signs

  • Diarrhea
  • Vomiting
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