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Pancreatitis and Lymphadenopathy

Case Of the Month

Pancreatitis and Lymphadenopathy

An 8-year-old FS Terrier Mix dog presented with symptoms of progressive vomiting and anorexia after having eaten bird seed 3 weeks prior. The clinical exam was uneventful except for mild scleral jaundice. The CBC and blood chemistry revealed severely elevated SAP elevated, elevated ALT, with mildly elevated AST, mildly elevated bilirubin, and mildly elevated cholesterol elevations.

An 8-year-old FS Terrier Mix dog presented with symptoms of progressive vomiting and anorexia after having eaten bird seed 3 weeks prior. The clinical exam was uneventful except for mild scleral jaundice. The CBC and blood chemistry revealed severely elevated SAP elevated, elevated ALT, with mildly elevated AST, mildly elevated bilirubin, and mildly elevated cholesterol elevations.

DX

Pancreatic adenocarcinoma with nodal metastasis.

Outcome

The patient was euthanized 2 weeks later due to persistence of signs despite medical treatment.

Clinical Differential Diagnosis

Pancreatitis, cholangiohepatitis, toxicity, biliary obstruction, GB mucocele, gastroenteritis, IBD.

Sampling

16-gauge US-guided biopsy of the right pancreatic base (see image) as well as the hypoechoic structure revealed in image 2 ( ln met) revealed pancreatic adenocarcinoma with nodal metastasis.

Sonographic Differential Diagnosis

Mixed echogenic nodular mass suggestive for pancreatic carcinoma, or severe pancreatic necrosis/pancreatitis. Aggressive regional lymphadenopathy would suggest a metastatic process.

Image Interpretation

A mixed hypo and hyperechoic mass is noted in the region of the pancreas. US-guided core biopsy is visible in both images at 2`oclock position (linear hyperechoic focus) in image 1 and in mid image in the hypoechoic lymph node in image 2.

Patient Information

Status : Complete

Images

Oreo_t_1_11252009022703Oreo_t_LN_2_11252009022721