04_00448 Snickers T Intestinal mass – small cell lymphoma

Case Study

04_00448 Snickers T Intestinal mass – small cell lymphoma

A 10-year-old NM DSH was presented for evaluation of intermittent vomiting and weight loss. On abdominal radiographs a slight accordion pattern was present. 

A 10-year-old NM DSH was presented for evaluation of intermittent vomiting and weight loss. On abdominal radiographs a slight accordion pattern was present. 

Sonographic Differential Diagnosis

Intestines – the findings are severe – DDX: inflammatory bowel disease vs. infiltrative neoplasia (small-cell lymphosarcoma vs. mast cell tumor – strong suspect IN THIS CASE) vs. dry FIP vs. fungal (histoplasmosis). Inflammatory bowel disease in cats can be chronic and longstanding, but in many cases will transition into small-cell lymphosarcoma and it is not possible with ultrasound alone to determine in this case whether the disease is benign or infiltrative.

Image Interpretation

Many to most loops of intestine are prominent and mildly to moderately thickened measuring 3.0-4.0mm (normal wall thickness ~ 2.2-2.5mm). Many have abnormal layering with prominent thickening of the muscularis layer and some loops have large fusiform mass lesions that are hypoechoic and in the mucosal layer. These masses are well circumscribed and localized to one side of the bowel loop (non-circumferential). A large section of the ileum has this mass lesion. Multiple mesenteric lymph nodes are mildly enlarged and normally shaped having homogenous hypoechoic echogenicity. The fat surrounding the mesenteric lymph nodes is severely hyperechoic.

DX

Small cell lymphoma

Outcome

None

Comments

Case courtesy of Marty Henderson, DVM, Sonovet, Inc.

Claudia Barton, DVM, ACVIM (Oncology & Internal Medicine

Clinical Differential Diagnosis

GIT – IBD, neoplasia, intussusception, foreign body, granulomatous enteritis, dietary hypersensitivity
Hyperthyroidism
Pancreas – pancreatitis, neoplasia
Renal disease

Sampling

Fine-needle biopsies of the mass lesions in the mucosal layer of the intestines demonstrated small cell lymphoma.

Patient Information

Gender : Male, Neutered
Species : Feline
Type of Imaging : Ultrasound
Status : Complete

Clinical Signs

  • Vomiting
  • Weight loss

Images

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Clinical Signs

  • Vomiting
  • Weight loss