Microscopic Interpretation: LYMPHOSARCOMA, LARGE CELL/LYMPHOBLASTIC FORM Comment: This is a diagnosis that warrants a cautious prognosis. Large cell lymphosarcoma that involves the G.I. tract typically responds poorly to chemotherapy while cases that do not have G.I. involvement will often respond with 6-18 month disease free intervals with chemotherapy.It is suspected that the ileocecal lymph node was aspirated, and if the tumor is confined to the node only chemotherapy will likely prove beneficial. Unfortunately there is a high probability of concurrent G.I. involvement as this is a common region for G.I. lymphosarcoma to originate.