Cholangiohepatitis with portal fibrosis in a 9 year old MN Jack Russell Terrier dog

Case Study

Cholangiohepatitis with portal fibrosis in a 9 year old MN Jack Russell Terrier dog

A 9-year-old MN Jack Russell Terrier dog was presented for a history of mild weight loss, and aggression. No abnormalities were noted on the CBC. Blood chemistry profile revealed mildly elevated total protein, SAP, and ALT enzymes activities. Urinalysis and serum bile acids were not performed.

A 9-year-old MN Jack Russell Terrier dog was presented for a history of mild weight loss, and aggression. No abnormalities were noted on the CBC. Blood chemistry profile revealed mildly elevated total protein, SAP, and ALT enzymes activities. Urinalysis and serum bile acids were not performed.

Sonographic Differential Diagnosis

Chronic inflammatory hepatopathy with fibrosis potentially hypomotile gall bladder.

Image Interpretation

The liver parenchyma was coarse with increased portal markings. The gall bladder presented minor excessive debris with echogenic wall.

DX

Chronic suppurative cholangiohepatitis with portal fibrosis and parenchymal collapse.

Outcome

Patient was lost to follow-up.

Comments

No video is available on this patient.

Clinical Differential Diagnosis

Cholangitis /cholangiohepatitis with a possible mucocoele. Hepatitis – acute suppurative, infectious (leptospirosis, toxoplasmosis), immune-mediated. Pancreatitis with secondary cholestasis and/or hepatitis. Neoplasia (primary vs. metastatic; hepatocellular adenoma, lymphoma, carcinoma, leiomyoma, leiomyosarcoma, mast cell tumor, histiocytic sarcoma, etc.) Change in behavior possibly secondary to abdominal discomfort associated with any of the above disease conditions.

Sampling

Ultrasound guided biopsy of the liver revealed a chronic suppurative cholangiohepatitis with portal fibrosis and parenchymal collapse.

Patient Information

Patient Name : River G
Gender : Male, Neutered
Species : Canine
Type of Imaging : Ultrasound
Status : Complete
Liz Wuz Here : Yes
Code : 03_00152

Clinical Signs

  • Aggression
  • Weight loss

Images

Riverliver

Blood Chemistry

  • Alkaline Phosphatase (SAP), High
  • ALT (SGPT), High
  • Total Protein, High

Clinical Signs

  • Aggression
  • Weight loss
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