Just some advise needed. I have a 10 yr old border collie diagnosed two years ago with myocarditis, first degree av block,some systolic dysftn. She has done very well long term on sotalol , mexiletine , fish oil. heart rate stays regular at 80. blood pressure stable echo mmode doesnt change. In last few months creat rising dilute urine looked at every reason for it have none. could perfusion be problem. Is there any use in manipulating anti arrhytmics?Appreciate input.
Just some advise needed. I have a 10 yr old border collie diagnosed two years ago with myocarditis, first degree av block,some systolic dysftn. She has done very well long term on sotalol , mexiletine , fish oil. heart rate stays regular at 80. blood pressure stable echo mmode doesnt change. In last few months creat rising dilute urine looked at every reason for it have none. could perfusion be problem. Is there any use in manipulating anti arrhytmics?Appreciate input.
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Hi!
If it was pre-renal
Hi!
If it was pre-renal (perfusion insufficiency), I would rather exect concentrated urine (with the exception of M. addison). The decreased concentration makes me think of chronic/degenerative disease. I haven’t seen mexitile or sotalol causing kidney insufficiency yet. And if you think of dogs with Sick Sinus Syndrome or AV-Block III – they hardly ever develop measurable kidney dysfunction as long as they are doing clinically well.
Extremely difficult to advise here because I haven’t seen the echo and the ECG-recordings. If the dog has not had any arrhythmia any more (Holter), there is indeed a chance to reduce the anti-arrhythmics. I would recommed a Holter, check Troponin I and then try – depending on the results – to change the therapy.
Peter
Excellent you answered my
Excellent you answered my question. I didn’t know how likely low perfusion would be. I will see how far the owner will go. thanks as always!
my pleasure!
my pleasure!