– 11 yr od MN Dandi Dinmont Terrier with history of pu/pd but clinically well
– no renal azotemia yet, urine SG 1.012, urine culture negative
– Cushings ruled-out on hormonal testing; adrenals normal on US
– proteinuria and hypertension (systolic BP 220-230)
– both kidneys have thick, hyperechoic renal cortices with renal cysts; capsule irregular in regions and pyelectasia
– 11 yr od MN Dandi Dinmont Terrier with history of pu/pd but clinically well
– no renal azotemia yet, urine SG 1.012, urine culture negative
– Cushings ruled-out on hormonal testing; adrenals normal on US
– proteinuria and hypertension (systolic BP 220-230)
– both kidneys have thick, hyperechoic renal cortices with renal cysts; capsule irregular in regions and pyelectasia
I would call this a chronic interstitial nephrosis pattern but is there anyway, other than biopsy to know if this glomerulonephritis, amyloidosis or other process and does it really change the way we would manage this case anyway?
Comments
Biopsy may help but at this
Biopsy may help but at this stage most likley going to get “chronic kidney disease” result that will not change the way to manage – renal diet, ACE inhibitors, anti-hypertensives (if BP does not come down). Biopsy may also push stable disease into clinical disease.
Thanks Remo – those were my
Thanks Remo – those were my thoughts as well – no point in rocking the boat!
You can fna the renal cortex
You can fna the renal cortex instead of bx and look for amyloid I think on a congo red stain but don’t recall the exact stain. Would have to check with your cytologist. you can assess the predominant inflammatory cell type too and I dont think you would cause further damage with a 25 or 22 g fna. But like Remo says its not likely going to help much but there is value in knowing more of course.