Saw about a 50 pound FS German Shepherd that was fairly lethargic, anemic, and had severe thrombocytopenia. For several years, the owners had a hard time keeping weight on her…generally ADR. Upon presentation, was walking around, quiet, alert, but not herself. Gradually declined over the course of 4 to 5 hours…then MM became pale…became agonal…had to humanely euthanize. I obtained some ultrasound images about an hour before euthanasia. Her ALT was only about 150 from what I recall. I am just wondering if this is what hepatocutaneous syndrome
Saw about a 50 pound FS German Shepherd that was fairly lethargic, anemic, and had severe thrombocytopenia. For several years, the owners had a hard time keeping weight on her…generally ADR. Upon presentation, was walking around, quiet, alert, but not herself. Gradually declined over the course of 4 to 5 hours…then MM became pale…became agonal…had to humanely euthanize. I obtained some ultrasound images about an hour before euthanasia. Her ALT was only about 150 from what I recall. I am just wondering if this is what hepatocutaneous syndrome, i.e. swiss cheese liver looks like? Thank you
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Hey Robb, IMO the swiss
Hey Robb, IMO the swiss cheese appearance of this liver can certainly look like HCS. If there were concurrent cutaneous lesions, it certainly could be. Generally with HCS, you see nonuniform increased parenchyma echogenicity with the irregular hypoechoic nodular changes that makes it look kinda moth eaten. The nodules, for the most part, look fairly well defined and diffuse. There is also some effusion between the liver lobes. I’m thinking more neoplasia here..with possible secondary bleeding in the abdomen or paraneoplastic anemia / ITP.
thank you….another somewhat
thank you….another somewhat unusual case….minimal platelets….walking around in the morning…and becoming agonal and bleeding out in the afternoon….and not your typical hemoabdomen presentation. It was also kind of unusual to see a liver like this with a minimal elevation in ALT.
Presntation is not typical
Presntation is not typical for HCS – would go for DDx that Mac suggested.
Looks liek a pronounced
Looks liek a pronounced nodular hyperplasia liver.
Good thought though.
Here are some HCS cases from the archive search
https://sonopath.com/members/case-studies/search?text=hepatocutaneous+&species=All