A 14-year-old NM Tonkinese was presented for evaluation of a monoclonal gammopathy on serum electrophoresis. Serum biochemistry showed azotemia and hyperproteinemia.
Case Study
08_00136 Amigo W Plasma cell tumor of spleen and liver
DX
Plasma cell sarcoma/myeloma of the liver and spleen.
Sonographic Differential Diagnosis
Splenic and hepatic infiltrative pattern with splenic nodules. 25-gauge ultrasound-guided FNA of the liver and spleen were performed without complications. Suspect lymphoma or multiple myeloma. Mast cell disease is also possible versus splenitis and reactive hepatopathy, which is less likely.
Image Interpretation
The spleen was significantly enlarged and measured 2.0 cm in width with mixed hyperechoic and hypoechoic nodular changes. A slight amount of free fluid was noted adjacent to the spleen.
The liver was uniformly hypoechoic to falciform fat, irregular and enlarged.
Outcome
None
Clinical Differential Diagnosis
Neoplasia – multiple myeloma, solitary plasmacytoma, lymphoma
Fungal disease
Renal disease – chronic kidney disease, obstructive uropathy, pyelonephritis
Sampling
Cytology of the liver and spleen revealed plasma cell sarcoma/myeloma of the liver and spleen.
Video
Patient Information
Gender :
Male, Neutered
Species :
Feline
Type of Imaging : Ultrasound
Status :
Complete
Images
Blood Chemistry
- Azotemia
- Total Protein, High
Special Testing
- Monoclonal gammopathy