I haven’t used Adequan for
I haven’t used Adequan for this purpose, but I have treated many many cats with interstitial cystitis with Cartrophen and the majority of cats have done well with it. They stopped urinating around the house. When they’d have a flare up, we’d repeat the cycle.

Thank you iscanvi, I will
Thank you iscanvi, I will pass this on to my doctors. Any suggestions to make these cats comfortable are very appreciated!

Was checking out Cartrophen
Was checking out Cartrophen and it is not available in the States as of yet, Adequan was noted as a similar-type drug to that of Cartrophen. Hopefully it will hit the States soon as another option for arthritis and sterile cystitis in cats!

Part of the proposed
Part of the proposed pathogenesis of feline interstitial/idiopathic/sterile cystitis is that the glycosaminoglycan layer on the bladder uro-epithelium is defective, allowing urine constituents to come in contact within the submucosa of the bladder and triggering inflammation. Therefore the rationale behind the use of drugs such as Adequan is that it improves the glycosaminoglycan layer within the bladder. Anecdotal evidence seems to support the use of glycosaminoglycan in the therapy.

Thank you for the wealth of
Thank you for the wealth of information Dr. Lobetti. What do you use in practice for your sterile cystitis cats?

I use diet (Hiils c/d or
I use diet (Hiils c/d or Royal Canin urinary and/or canned food), amitriptyline, and r the glucosamine and chondroitin sulfate supplements (Cosequin and the like).

Thanks Dr.Lobetti.
Thanks Dr.Lobetti.

I use quite a bit of
I use quite a bit of glucosamine in cats with idiopathic cystitis, and I think it mostly helps the owner and vet feel like they are doing something (besides increasing water intake). I think the studies out there have not shown good evidence for it, but I use it in lieu of prescribing antibiotics.

Thank you Liz.
Thank you Liz.