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Cushings testing warranted?

Sonopath Forum

Cushings testing warranted?

–  12 year old Miniature Schnauzer

–  Labs done because dog has increased it’s water consumption noticabley. ALP 433 U/L, ALT 227 U/L, Glucose 198 but nomral Fructosamine, USG 1.024

–  Ultrasound revealed liver nodules (FNA’s – vacuolar hepatopathy), one lymph node enlarged near kidney (FNA – mild lymphoid hyperplasia), and adrenals measuring: R = 2.65 x .55 and .61cm, L = 1.92 x 0.65 and 0.52 cm

Question:  Is it indicated to test for Cushings with adrenals this size and these labs?

Thanks

–  12 year old Miniature Schnauzer

–  Labs done because dog has increased it’s water consumption noticabley. ALP 433 U/L, ALT 227 U/L, Glucose 198 but nomral Fructosamine, USG 1.024

–  Ultrasound revealed liver nodules (FNA’s – vacuolar hepatopathy), one lymph node enlarged near kidney (FNA – mild lymphoid hyperplasia), and adrenals measuring: R = 2.65 x .55 and .61cm, L = 1.92 x 0.65 and 0.52 cm

Question:  Is it indicated to test for Cushings with adrenals this size and these labs?

Thanks

Comments

EL

A small % of PDH dogs will

A small % of PDH dogs will have normal adrenals on US… around 10% or less last I checked. If USG is dropping < 1.020 then I would do an ACTH stim and BP or run a full adrenal panel U of Tennessee but this test still has some controversy with it but if the patient looks endocrine and the tests support it then treatment would be warranted. Perceivable PUPD is usually < 1.020 so be sure there isnt pollakiuria instead caused by a uti or similar… salty diet maybe..?

leonaclown

Thanks Eric!

Thanks Eric!

rlobetti

Is the patient polyphagic

Is the patient polyphagic and/or polyuric as well? With the age should also consider early kidney disease.

leonaclown

Not polyuric or -phagic. He
Not polyuric or -phagic. He lost another pet to chronic kidney disease recently, so we’ll stay on this one close. Thanks