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Dilated Cardiomyopathy (DCM) in a 9 year old MN Doberman dog

Case Study

Dilated Cardiomyopathy (DCM) in a 9 year old MN Doberman dog

A 9-year-old MN Doberman was presented for exercise intolerance, lethargy, and anorexia. Physical examination found a grade IV/VI heart murmur in the area of the mitral valve. CBC and blood chemistry were both within normal limits. Thoracic radiographs showed generalized cardiomegaly, a tall heart, with a prominent left atrium, mild pulmonary congestion, and hilar lung edema. ECG revealed Paroxysmal Ventricular tachycardia and VPC’s. Blood pressure measurements were within normal range.

A 9-year-old MN Doberman was presented for exercise intolerance, lethargy, and anorexia. Physical examination found a grade IV/VI heart murmur in the area of the mitral valve. CBC and blood chemistry were both within normal limits. Thoracic radiographs showed generalized cardiomegaly, a tall heart, with a prominent left atrium, mild pulmonary congestion, and hilar lung edema. ECG revealed Paroxysmal Ventricular tachycardia and VPC’s. Blood pressure measurements were within normal range.

DX

Dilated cardiomyopathy.

Sonographic Differential Diagnosis

Dilated cardiomyopathy.

Image Interpretation

The echocardiogram for this patient presented a left atrium of excessive size with anechoic content. No evidence of “smoke” or thrombotic activity was noted. The atrial septum was deviated toward the right atrium consistent with left sided overload. The LA/AO ratio was excessive for dogs. The cranial and caudal mitral valve leaflets demonstrated mildly vegetative contour. End point to septal separation was excessive consistent with dilated cardiomyopathy. The left ventricle demonstrated mildly excessive volume, and normal to subnormal septal and free wall diastolic thicknesses. Ventricular function was deemed subnormal expressed by the fractional shortening measurement listed below. The aortic outflow tract revealed direct laminar flow along the ventricular septum with subnormal outflow velocity. Periaortic tissue was uniform and of normal echogenicity. No inconsistencies were revealed regarding the presence of an aortic body tumor or chemodectoma. The right atrium was enlarged. Tricuspid valve insufficiency was noted and was significant at 3.1 m/sec. This is consistent with pulmonary hypertension. The right ventricle demonstrated normal size (1/3 diameter of the left ventricle), morphology, and kinetic activity. No evidence of heartworm or infiltrative disease was noted. The pulmonary artery was dilated. The myocardium throughout the heart was uniformly echogenic without evidence of significant fibrosis, infiltrative disease (lymphoma, hemangiosarcoma) or ischemic events (infarcts). Endo, epi, pericardial and pleural tissue was uniformly hyperechoic to the myocardium without the presence of effusions. Tachyarrhythmia was noted during the exam in this patient. An electrocardiogram would be warranted. Tricuspid insufficiency velocity 3.1 m/sec.

Outcome

Recommendation: start treatment with Pimobendan, Lasix, Enalapril, and Aspirin. A gradual change to a geriatric diet was also advised. A recheck echocardiogram in three days was recommended with the possible addition of anti-arrythmic therapy, if warranted, along with another echocardiogram, blood pressure check, and thoracic radiographs in one week.

Patient Information

Patient Name : Barkley G
Gender : Male, Neutered
Species : Canine
Type of Imaging : Ultrasound
Status : Complete
Liz Wuz Here : Yes
Code : 15-00019

Clinical Signs

  • Anorexia
  • Exercise intolerance
  • Lethargy

Exam Finding

  • Heart Murmur

Images

DCMLongAxisComparisonofSystoleandDiastoleLVEPSS15_00019_EPSSDilatedLV

Clinical Signs

  • Anorexia
  • Exercise intolerance
  • Lethargy