Ectopic thyroid carcinoma (embryonal development involves the region of the base of the tongue), laryngeal carcinoma, osteosarcoma and chondrosarcoma of the hyoid bone are likely differential diagnoses amongst others.
Final diagnosis warrants tumor sampling. The prognosis for curative surgical resection is poor owing to the infiltrative growth into critical structures. However, at least cytoreductive surgery followed by radiative treatment and/or adjuvant chemotherpy may be an option depending on the tumor type.
The computed tomography is negative for regional and distant metastatic spread.