03-00232 Yuki N Malignant neoplasia, liver—NEED C—NO IMAGES—–

Case Study

03-00232 Yuki N Malignant neoplasia, liver—NEED C—NO IMAGES—–

A 14-year-old NM Shih Tzu was presented for evaluation of abdominal pain and hematuria. Abnormalities on CBC and serum biochemistry were leukocytosis, severe anemia, and moderate elevation of ALP and ALT activity.

A 14-year-old NM Shih Tzu was presented for evaluation of abdominal pain and hematuria. Abnormalities on CBC and serum biochemistry were leukocytosis, severe anemia, and moderate elevation of ALP and ALT activity.

Sonographic Differential Diagnosis

Splenic masses and liver masses. Multicentric neoplasia, likely sarcoma or similar neoplasia.

Image Interpretation

The liver presented a left medial mass. The liver mass did not appear overtly resectable given the impingement and wrapping of the porta hepatis. The spleen presented a heterogeneous mass that measured 5+ cm with microcystic changes. The spleen also presented other nodular changes with target type appearance and other masses at the cranial pole. The kidneys revealed largely normal size and structure, corticomedullary definition and ratio (cortex 1/3 of medulla) were essentially maintained with some age related loss of curvilinear pattern. The cortices presented largely uniform texture with some age related echogenic changes that are not likely of clinical significance at this time. Medullary echogenicity differed distinctly from that of the cortex and no evidence or dilation could be seen. The capsules were acceptably uniform for this age patient without dramatic irregularities. Mineralization was noted in the kidneys. The left kidney measured 5.1 cm.

Comments

Was the second FNA REALLY the kidney and not the spleen? f

Clinical Differential Diagnosis

Hematuria: bladder (neoplasia/trauma/cystitis), renal (neoplasia/trauma/vascular defect, idiopathic renal hematuria), hemorrhagic diathesis. Liver: acute hepatopathy, toxins, viral/bacterial/fungal hepatitis, abscess, granulomatous disease, neoplasia. Splenic neoplasia/torsion.

Sampling

Liver: Moderate mixed inflammation with malignant neoplasia. Kidney: Malignant neoplasia with moderate mixed inflammation.

Patient Information

Species : Canine
Type of Imaging : Ultrasound

Clinical Signs

  • Abdominal Pain
  • Hematuria

Blood Chemistry

  • Alkaline Phosphatase (SAP), High
  • ALT (SGPT), High

CBC

  • RBC, Low
  • WBC, High

Clinical Signs

  • Abdominal Pain
  • Hematuria