– 8yr old MN Abyssinian presented for recurrent signs of straining  to urinate, bloody urine – signs typical of FUS but not blocked; abdominal rads normal

– urine culture negative   BUN 14.6 (5-12.9)  CRE 241 (53-212)  urine SG 1.036

– first ultrasound performed January 3rd showed a fairly empty UB with thickened walls which was difficult to interpret due to lack of distension however there was an inflammatory pattern (I think) in the fat around the UB; presumptive treatment  idiopathic cystitis started

– SI at the time normal

– 8yr old MN Abyssinian presented for recurrent signs of straining  to urinate, bloody urine – signs typical of FUS but not blocked; abdominal rads normal

– urine culture negative   BUN 14.6 (5-12.9)  CRE 241 (53-212)  urine SG 1.036

– first ultrasound performed January 3rd showed a fairly empty UB with thickened walls which was difficult to interpret due to lack of distension however there was an inflammatory pattern (I think) in the fat around the UB; presumptive treatment  idiopathic cystitis started

– SI at the time normal

– pet presented Jan 23rd due to perceived “weakness” by the owner – losing weight and decreasd appetite; cystitis signs resolved but took a while to respond to therapy

– repeat ultrasound: irregular thickening of the urinay bladder in the ventral wall in the trigone region; SI now showing an increase in muscularis layer;  jejnunal LN moderately enlarged – no other LN’s seen (DDX: IBD, lymphoma)

– quick chest scan” normal LA; no effusion, masses seen

I have scheduled biopsy of the bladder wall and full thickness biopsies of the SI.

Opinion on the bladder lesion?