Abnormal pancreas in a 9 yr old DSH

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Abnormal pancreas in a 9 yr old DSH

      • Weight loss and intermittent anorexia since July 2021. No vomiting or diarrhea.
      • Mild hyperglycemia, mild persistent ALP elevation
      • Abdominal ultrasound shows an enlarged, hypoechoic, pancreas with an irregular capsule and adjacent echogenic fat.  The liver shows increased echogenicity.  The gallbladder has a thickened, echogenic wall. The spleen is rounded in shape with normal parenchyma.
      • US guided FNA was performed on the liver and pancreas.  Liver cytology shows mild to moderate hepatic lipidosis.  
      • Pancreatic cytologys shows: “Minimally atypical pancreatic tissue without evidence of inflammation or necrosis;These results suggest a benign pancreatic nodular hyperplasia. A well differentiated pancreatic adenocarcinoma could be possible, but I would expect a mass lesion to be present rather than a more diffuse enlargement. If you clinically suspect carcinoma to be more likely and there is no obvious dissemination in the thorax or abdomen that would preclude surgical excision, please consider histopathological analysis.”
      • Just wondering what your thoughts are on this pancreas…Thanks!

Comments

rlobetti

I would be concerned about

I would be concerned about pancreatic neoplasia. Would not expected nodular hyperplasia to result in the presenting clinical signs. Needs a Tru-cut/wedge biopsy for a specific answer.

Electrocute

Thank you Remo.

Thank you Remo.

EL

I agree on the tru cut bx on

I agree on the tru cut bx on this one ideally but fna may give some info. There is an inflammatory pattern around the capsule.

Electrocute

Thanks Eric.  An FNA was

Thanks Eric.  An FNA was already done.  Please see the pathologist’s comments in the original post.

EL

ah yes then core bx is the

ah yes then core bx is the way to go.

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