Transitional cell carcinoma of the prostate and lymph node in a 13 year old MN Maltese

Case Study

Transitional cell carcinoma of the prostate and lymph node in a 13 year old MN Maltese

A 13-year-old neutered male Maltese dog was presented for hematuria. Survey radiographs were within normal limits. Abnormalities on serum biochemistry included elevated ALP activity and cPL (321).

A 13-year-old neutered male Maltese dog was presented for hematuria. Survey radiographs were within normal limits. Abnormalities on serum biochemistry included elevated ALP activity and cPL (321).

Sonographic Differential Diagnosis

Prostatic mass with cystic portions. This mass appears to invade and destroy the prostatic urethra with expansive mineralizing neoplastic tissue.

Image Interpretation

The prostate in this patient presented a mineralizing mass that measured 3.21 x 2.25 cm with sublumbar lymphadenopathy that measured 2 x 1.5 cm. There was a pericapsular inflammatory pattern. The prostatic mass demonstrated polypoid proliferation into the cystourethral junction as well. Cystic portions of the prostatic mass were also noted; this may represent dramatically proliferative tissue.
Urinary bladder debris was noted. The bladder wall was unremarkable other than the polypoid changes at the cystourethral junction.

DX

Transitional cell carcinoma of the prostate with local lymphadenopathy

Outcome

None

Comments

Potential drainage of the cystic regions of the prostate can be considered to provide palliative treatment. Stent placement is a possibility in this case. Deramaxx and Enrofloxacin are recommended in the meantime.

Clinical Differential Diagnosis

Lower urinary tract disease – chronic bacterial cystitis, neoplasia, uroliths, granulomatous cystitis, polyploid cystitis. Prostatic disease – neoplasia, abscess. Upper urinary tract disease – neoplasia, renolith, pyelonephritis.
Increased ALP – hepatic neoplasia, nodular regeneration, Cushing’s disease, disease of the gall bladder (cholecystitis, mucocele), pancreatic/duodenal disease.

Sampling

Ultrasound-guided FNAs of the prostate and lymph nodes revealed transitional cell carcinoma.

Patient Information

Patient Name : Snowball H
Gender : Male, Neutered
Species : Canine
Type of Imaging : Ultrasound
Status : Complete
Liz Wuz Here : Yes
Code : 09_00064

Clinical Signs

  • Hematuria

Images

prost_measbetter_trigbladderln

Blood Chemistry

  • Alkaline Phosphatase (SAP), High

Clinical Signs

  • Hematuria

Special Testing

  • cPLI Positive
Skip to content