hepatic architecture

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hepatic architecture

Snickers has been picky with food recently (until owner just introduced LD, which he thankfully seems to like so far).  He has had intermittent diarrhea w/ some blood.    Clostridial overgrowth on fecal smear.  Diarrhea responded to antibiotics.  Has been having a number of senior moments.

Snickers has been picky with food recently (until owner just introduced LD, which he thankfully seems to like so far).  He has had intermittent diarrhea w/ some blood.    Clostridial overgrowth on fecal smear.  Diarrhea responded to antibiotics.  Has been having a number of senior moments.
Blood work was drawn on 8/3 and showed marked liver enzyme elevation.  AST 251, ALT 1803, ALP 5830, GGT 40 and T bili is normal at 0.3.  Glucose is 69, albumin normal at 3.1.  Cholesterol 441.  CBC and thyroid normal.  Had been on Riamdyl for a soft tissue injury short term, but that was discontinued as soon as blood work seen.  rDVM and owner have also discussed performing bile acids test. 

Unfortunately, owner declined a FNA or tru cut tonight.  I am just wanting some feedback on your top rule outs looking at the architecture of the liver.  It is hyperechoic to the spleen and appears more homogenous than normal w/ some attenuation of vasculature.  No aberant vessels or effusion.  Adrenal lands are normal size and rest of abdomen was unremarkable, but was also wondering what you think of the stomach video – the lumenal contents look abdormal to me. 

Comments

EL

Looks like food in th e

Looks like food in th e stomach kibble and such in second video. There is a CAH pattern and increased portal markings (see my attached short arrow) and gb sludge (long arrow) wiht some Gb overdistention but nit mucocele yet. I would do a bile acid profile see if some of this cognitive issue is ammonia related. If so the start on lactulose metronidazole actigal and royal canine hepatic support or similar.

 

 

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