- 5 year old FS Greyhound presented to rDVM 3 weeks ago for neck pain, lethargy, and weight loss
- PE showed petechia and echymoses
- Blood work showed a severe thromboyctopenia (10,000), rest of labwork was wnl included 4DXT-all neg
- The patient was treated with prednisone, atopica, famotidine, and doxycycline
- The platelet count increased to 250,000 then decreased to 110,000 after the owners decreased the pred dose on their own.
- 5 year old FS Greyhound presented to rDVM 3 weeks ago for neck pain, lethargy, and weight loss
- PE showed petechia and echymoses
- Blood work showed a severe thromboyctopenia (10,000), rest of labwork was wnl included 4DXT-all neg
- The patient was treated with prednisone, atopica, famotidine, and doxycycline
- The platelet count increased to 250,000 then decreased to 110,000 after the owners decreased the pred dose on their own.
- Abdominal ultrasound shows splenomegaly, increased splenic echogenicity, coarse parenchyma, and some mild congestion of the splenic and hepatic veins.
- Chest radiographs are nonremarkable. Echocardiogram shows no cardiac masses and no pleural or pericardial effusions.
- Cardiac measurements are as follows: IVSd=16.1, LVIDd=50, LVPWd=16, IVSs=17, LVIDs=39, LVPWs=17, FS=23%.
- My primary differentials are immune mediated thrombocytopenia (primary and secondary), neoplasia (LSA, MCT), and less likely bone marrow disease (all other cell lines are within normal limits)
- The confusing part is this dog continues to lose weight (10-12% BW) despite a good appetite. Can ITP cause weight loss? Could this be atopica, or is neoplasia more likely? Splenic fna’s are pending.
