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Subnormal right kidney, loss of corticomedullary definition with haematuria

Sonopath Forum

Subnormal right kidney, loss of corticomedullary definition with haematuria

Hi guys,

Just wanted a second opinion on this kidney. 10 year old male neutered domestic shorthair came in for dental prophylaxis. Incidental finding of haematuria on urinalysis, no clinical signs. Haematuria persisted after 2 weeks.

Urinalysis showed USG: 1.049, PH: 6 Protein 2+, Blood 4+ and no growth after 48 hours. Blood work was unremarkable.

The right kidney was subnormal in size with complete loss of corticomedullary definition. 

Hi guys,

Just wanted a second opinion on this kidney. 10 year old male neutered domestic shorthair came in for dental prophylaxis. Incidental finding of haematuria on urinalysis, no clinical signs. Haematuria persisted after 2 weeks.

Urinalysis showed USG: 1.049, PH: 6 Protein 2+, Blood 4+ and no growth after 48 hours. Blood work was unremarkable.

The right kidney was subnormal in size with complete loss of corticomedullary definition. 

The left kidney showed hyperechoic triangular striations towards the medulla in the caudal pole with focal cortical depression, potentially secondary to chronic renal infarct.

Bladder had mild thickeneding on the cranio-ventral aspect.

Questions:

What are the differentials for the right kidney in a 10 year old cat? Can this be congenital renal dysplasia?

Can the changes of the kidneys caused the haematuria?

 Would you do a FNB on the right kidney?

Comments

EL

Big kidney little kidney

Big kidney little kidney syndrome. The right kidney is progressively infarcting down to a raisin owing to usually interstitial nephrosis, stone moving or pyelonephritis. Systemic thromboembolic events can do this as well but when throwing clots to kidneys they usually dont live long enough to scar up pretty infarcts like these. The opposite kidney usually swells a bit with compensatory hypertrophy but may also undergo the same process (like these with the smaller infarcts) with the same result til renal failure occurs when 65-70% of functional parenchyma is compromised. Nice image set.

EL

Big kidney little kidney

Big kidney little kidney syndrome. The right kidney is progressively infarcting down to a raisin owing to usually interstitial nephrosis, stone moving or pyelonephritis. Systemic thromboembolic events can do this as well but when throwing clots to kidneys they usually dont live long enough to scar up pretty infarcts like these. The opposite kidney usually swells a bit with compensatory hypertrophy but may also undergo the same process (like these with the smaller infarcts) with the same result til renal failure occurs when 65-70% of functional parenchyma is compromised. Nice image set.

rlobetti

Possibly can be a cause for

Possibly can be a cause for the hematuria but kidney looks fairly inactive – consider interstitial cystitis. Dysplasia not likely as only one kidney affected.  

rlobetti

Possibly can be a cause for

Possibly can be a cause for the hematuria but kidney looks fairly inactive – consider interstitial cystitis. Dysplasia not likely as only one kidney affected.  

randyhermandvm

Make sure you check the

Make sure you check the trigone and as much of the urethra as you can see

randyhermandvm

Make sure you check the

Make sure you check the trigone and as much of the urethra as you can see

lookpris

Thank you everyone for the

Thank you everyone for the feedback!

So just to clarify: the right kidney is most likely caused by chronic renal disease. The bloods are normal and patient have no clinical signs due to compensating left kidney?

Does the right kidney warrant a biopsy to get a diagnosis given there’s no evidence of inflammation or just monitor it via ultrasound. If the latter: what are monitoring for? More infarcts? Size? 

@randyhermandvm: Are we mainly looking for uroliths or calculi in the trigone and urethra? I couldn’t see any abnormalities.

lookpris

Thank you everyone for the

Thank you everyone for the feedback!

So just to clarify: the right kidney is most likely caused by chronic renal disease. The bloods are normal and patient have no clinical signs due to compensating left kidney?

Does the right kidney warrant a biopsy to get a diagnosis given there’s no evidence of inflammation or just monitor it via ultrasound. If the latter: what are monitoring for? More infarcts? Size? 

@randyhermandvm: Are we mainly looking for uroliths or calculi in the trigone and urethra? I couldn’t see any abnormalities.

randyhermandvm

Looking for any pathology

Looking for any pathology including stones, masses, strictures etc

I figured you probably looked- but I just wanted to make sure.

randyhermandvm

Looking for any pathology

Looking for any pathology including stones, masses, strictures etc

I figured you probably looked- but I just wanted to make sure.

EL

Until 65-75% of the

Until 65-75% of the functional parenchyma is damaged you won’t have renal failure and if the active process has stopped then clinical signs at the time of exam won’t be present either but this cat has had some period of malaise when undergoing than acute-on-chronic crisis to get to this point. You could bx the RK but I dont know how much it will help the overall management. If there were a concurrent inflammatory pattern with the rk (not present in these images) then I would remove it at this point and bx the LK to assess the active process. You can check infectious tites and see if there is a systemic bug that may be linked to this…

lookpris

Aweseome! Thanks EL! 🙂

Aweseome! Thanks EL! 🙂

EL

Until 65-75% of the

Until 65-75% of the functional parenchyma is damaged you won’t have renal failure and if the active process has stopped then clinical signs at the time of exam won’t be present either but this cat has had some period of malaise when undergoing than acute-on-chronic crisis to get to this point. You could bx the RK but I dont know how much it will help the overall management. If there were a concurrent inflammatory pattern with the rk (not present in these images) then I would remove it at this point and bx the LK to assess the active process. You can check infectious tites and see if there is a systemic bug that may be linked to this…

lookpris

Aweseome! Thanks EL! 🙂

Aweseome! Thanks EL! 🙂

EL

U bet! If you happen to get

U bet! If you happen to get histopath please add it to the thread.

 

EL

U bet! If you happen to get

U bet! If you happen to get histopath please add it to the thread.