- strange looking spleen in a 14 yo N Terrier Mix with hx HAC (treated with Lisodren) x 1 yr
- Recent hx of anemia, vomiting (pancreatitis), inc ALP & ALT
Her exam showed left adrenal capsular expansion with phrenic vein invasion (could not be seen to invade CVC), evidence of pancreatitis and a very strange looking spleen. The spleen had multiple hyperechoic nodules, with distortion of the capsule. My question is whether or not the spleen is causing the anemia or if it is from chronic disease.
- strange looking spleen in a 14 yo N Terrier Mix with hx HAC (treated with Lisodren) x 1 yr
- Recent hx of anemia, vomiting (pancreatitis), inc ALP & ALT
Her exam showed left adrenal capsular expansion with phrenic vein invasion (could not be seen to invade CVC), evidence of pancreatitis and a very strange looking spleen. The spleen had multiple hyperechoic nodules, with distortion of the capsule. My question is whether or not the spleen is causing the anemia or if it is from chronic disease.
Unfortunately owner would not allow FNA & dog was euthanized.
So what do these nodules mean in a chronically ill patient? Seen this before but never so many (they are not I don’t think simply plaques)
Thanks! Tomie
Comments
Splenic disease can often
Splenic disease can often result in anemia – from abnormal circulation causing a degree of hemolysis or from secondary immune-mediated hemolytic anemia. Both of these should be of a regenerative nature. Anemia of chronic disease/inflammation is also possible but generally tends to be non-regenerative to poorly/inappropriate regeneration.
Splenic disease can often
Splenic disease can often result in anemia – from abnormal circulation causing a degree of hemolysis or from secondary immune-mediated hemolytic anemia. Both of these should be of a regenerative nature. Anemia of chronic disease/inflammation is also possible but generally tends to be non-regenerative to poorly/inappropriate regeneration.
These splenic lesions look
These splenic lesions look like lipogranulomas or maybe sequelae from splenitis. The best dx move at this point would be to provide a cytologist with fresh blood smear and cbc, fna of the spleen and bone marrow fna or bx. That should clear anything up. That being said i have seen mast cell spleens look like this but they are usually swollen and the patient would have clinical signs as not much mct is needed to give significant clinical signs.
These splenic lesions look
These splenic lesions look like lipogranulomas or maybe sequelae from splenitis. The best dx move at this point would be to provide a cytologist with fresh blood smear and cbc, fna of the spleen and bone marrow fna or bx. That should clear anything up. That being said i have seen mast cell spleens look like this but they are usually swollen and the patient would have clinical signs as not much mct is needed to give significant clinical signs.