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Cranial Abdomen Mass

Case Of the Month

A 16-year-old FS DSH cat with history of diabetes and hyperthyroidism was presented due to vomiting, diarrhea, and anorexia. Physical exam found poor body condition and weight loss. Urinalysis showed SG of 1.017, proteinuria, and hematuria. A coagulation panel was mildly elevated.

A 16-year-old FS DSH cat with history of diabetes and hyperthyroidism was presented due to vomiting, diarrhea, and anorexia. Physical exam found poor body condition and weight loss. Urinalysis showed SG of 1.017, proteinuria, and hematuria. A coagulation panel was mildly elevated.

DX

Poorly differentiated adenocarcinoma. (Spleen and adhered omentum with no recognizable pancreatic tissue present).

Outcome

Clinical recommendations included chest radiographs, assessment of the cytology followed by exploratory surgery with aggressive left pancreatectomy as well as exploration for any evidence of metastatic disease that was not noted on ultrasound. However, no metastatic disease was overtly suspected and the lesion appeared to be largely isolated to the left pancreatic limb with minor capsular escape. Pancreatic carcinoma was the primary differential, however a granulomatous lesion was also a possibility from a sonographic aspect though less likely. The patient underwent exploratory surgery. The lesion was resected surgically even though it was wrapped around the splenic vessels. A concurrent splenectomy was also performed. The patient unfortunately died suddenly post-op after succesful resection. Thromboembolic episode was suspected.

Comments

We at SonoPath.com would like to thank Andi Parknson RDMS & Rachel Brillhart RDMS of Intrapet Imaging, Baltimore, MD and their clients and collaborators, Dr. Alicia McMichaels (primary) and Dr. Jonathan Kaufman of Eastern Animal Hospital, Baltimore, MD, USA (http://easternanimalhospital.com/) for their excellent clinical and surgical management of this case. Moreover, their continual support of diagnostic efficiency in veterinary medicine through direct and remote support in their operations in exemplary and paramount to success in this field. Even though the outcome was not a positive one in this patient, the diagnostic workflow allowed the owner to make solid and efficient decisions for their pet with minimal suffering or delay in the diagnostic process in defining this aggressive neoplastic pathology.

Clinical Differential Diagnosis

Pancreas clinical signs- pancreatitis, neoplasia, abscessation. Uncontrolled hyperthyroidism. G.I. clinical signs- IBD, neoplasia, intussusception, foreign body, ulceration, infectious (viral/bacterial/parasites). Renal clinical signs- renoliths, neoplasia. Interstitial cystitis.

Sampling

US-guided FNA of the pancreatic mass.

Sonographic Differential Diagnosis

Pancreatic mass, left limb. This appears resectable. Minor adjacent lymphadenopathy.

Image Interpretation

A left, caudal pancreatic mass was noted in this patient and measured 4.0 cm with moderate complexity attached to the left lobe of the pancreas. Hyperechoic surrounding fat was also noted. This is consistent with extension of the neoplastic process or associated inflammation. This appears potentially resectable. An exploratory surgery is recommended with removal of the adjacent lymph node measuring 1.5 cm (Not seen in these images). The right limb of the pancreas was mildly heterogenous, yet unremarkable. There was no overt evidence of metastatic disease noted. FNA was obtained of the pancreatic mass. The pancreas in this patient presented severely dilated duct at 0.49 cm with heterogenous, irregular parenchymal changes and tortuous pancreatic duct. The caudal abdomen revealed a cystic or irregular lymph node that measured 1.48 x 1.15 cm. This is likely jejunal lymph node with distorted architecture. Granulomatous disease or possible neoplasia may be present. FNA was recommended.

UA Specific Gravity Range

1.017

Video

Patient Information

Patient Name : Shirley M
Gender : Female, Spayed
Species : Feline
Status : Complete
Code : 05_

Clinical Signs

  • Anorexia
  • Diarrhea
  • Vomiting

History

  • Anorexia
  • Diabetes, controlled
  • Diarrhea
  • Hyperthyroidism
  • Vomiting

Exam Finding

  • Weight loss

Images

feline_panc_mass_shirleyfeline_panc_fna_shirley

Clinical Signs

  • Anorexia
  • Diarrhea
  • Vomiting

Urinalysi

  • Blood Present
  • Protein Present