US and CYT – Multiple myeloma diagnosed by splenic FNA/cytology in an 8 year old MN DSH cat with hyperglobulinemia

Case Study

Case Study

US and CYT – Multiple myeloma diagnosed by splenic FNA/cytology in an 8 year old MN DSH cat with hyperglobulinemia

An 8-year-old NM DSH with a history of azotemia was presented for evaluation. Abnormalities on serum biochemistry were azotemia (BUN 58, creatinine 3.4), hyperproteinemia (22.8), hypoalbuminemia (1.9), and severe hyperglobulinemia (20.9). 

An 8-year-old NM DSH with a history of azotemia was presented for evaluation. Abnormalities on serum biochemistry were azotemia (BUN 58, creatinine 3.4), hyperproteinemia (22.8), hypoalbuminemia (1.9), and severe hyperglobulinemia (20.9). 

DX

Plasma cell proliferation consistent with multiple myeloma

Sonographic Differential Diagnosis

multiple myeloma
chronic infectious disease- less likely
immune stimulations – less likely

Image Interpretation

The spleen was enlarged with scalloping contour with micronodular changes and measured 1.5 cm in width.

Clinical Differential Diagnosis

Renal – chronic kidney disease, granulomatous nephritis, neoplasia
FIP
Multiple myeloma
Lymphoma

Sampling

FNA/cytology of the spleen was performed.and revealed plasma cell proliferation consistent with multiple myeloma.

Patient Information

Patient Name : Oliver Duran/ACC Flanders
Gender : Male, Neutered
Species : Feline
Type of Imaging : Ultrasound
Status : Complete
Liz Wuz Here : Yes

Clinical Signs

  • "Not Doing Right"
  • Weight loss

History

  • Azotemia

Images

screen_shot_2016-04-30_at_10screen_shot_2016-04-30_at_10screen_shot_2016-04-30_at_10

Blood Chemistry

  • Albumin, Low
  • BUN high
  • Creatinine, High
  • Globulin, High
  • Total Protein, High

CBC

  • WBC, High

Clinical Signs

  • "Not Doing Right"
  • Weight loss
Skip to content