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Systemic mycosis with acute renal failure in a 2-year-old MN German Shepherd

Case Study

Systemic mycosis with acute renal failure in a 2-year-old MN German Shepherd

A 2-year-old MN German Shepherd was presented for anorexia, lethargy, exhibiting acute renal failure and the following labs: Azotemia (BUN >130; Creat 9.9), USG=1.012, Hyperblilrubinemia, and Leukocytosis (52,000).

A 2-year-old MN German Shepherd was presented for anorexia, lethargy, exhibiting acute renal failure and the following labs: Azotemia (BUN >130; Creat 9.9), USG=1.012, Hyperblilrubinemia, and Leukocytosis (52,000).

Image Interpretation

Abdominal US revealed an enlarged, heterogenous spleen and bilateral hydronephrosis with no obvious blockages/masses noted. *Urinary catheter was easily passed.The renal pelvic dilation was remarkable and the there was obvous echogenic, fingerlike projections into the pelvis. There were significant corticomedullary changes as well.

DX

Systemic mycosis with acute renal failure.

Outcome

Patient was unfortunately euthanized and no further testing was done to further identify the fungal isolate.

Clinical Differential Diagnosis

The RDVM was treating for UTI and possible lepto (Pen G and Baytril at the time) with no response.

Sampling

Patient was lightly sedated with 1/4 torb dose and a 25 gauge 3 1/2″ needle was guided into the left renal pelvis. Urine pellet was obtained and diff-quick stain revealed abundant septated hyphae. Samples were sent to reference lab for confirmation of fungal infection consistent with Aspergillus species.

UA Specific Gravity Range

1.012

Patient Information

Gender : Male, Neutered
Species : Canine
Type of Imaging : Ultrasound
Status : Complete

Clinical Signs

  • Anorexia
  • Lethargy

Images

Blood Chemistry

  • Azotemia
  • Total Bilirubin, High

CBC

  • WBC, High

Clinical Signs

  • Anorexia
  • Lethargy