Splenic thrombus in an 11 year old FS Labrador mix

Case Study

Splenic thrombus in an 11 year old FS Labrador mix

An 11-year-old FS Labrador Retriever mix with history of hypothyroidism was presented for weakness. The physical exam was unremarkable other than mild tachypnea under exertion. On urinalysis, trace proteinuria and hematuria and moderate epithelial cells were present. CBC and blood chemistry showed lymphopenia, basophilia, eosinophilia, thrombocytopenia, elevated ALP and elevated AST activity, elevated CK, and hypertriglyceridemia. An EKG done one month later showed sinus rhythm with sustained idioventrical rhythm.

An 11-year-old FS Labrador Retriever mix with history of hypothyroidism was presented for weakness. The physical exam was unremarkable other than mild tachypnea under exertion. On urinalysis, trace proteinuria and hematuria and moderate epithelial cells were present. CBC and blood chemistry showed lymphopenia, basophilia, eosinophilia, thrombocytopenia, elevated ALP and elevated AST activity, elevated CK, and hypertriglyceridemia. An EKG done one month later showed sinus rhythm with sustained idioventrical rhythm. Blood pressure was within normal range The patient was treated with 40 mg Sotolol twice daily. Presented for ultrasound due to acute onset hind limb weakness.

DX

Splenic thrombus, idiopathic.

Sonographic Differential Diagnosis

Splenic thrombus, idiopathic. Probable local or systemic hypercoagulable state.

Image Interpretation

The spleen presented a relatively normal size however a 4cm long splenic vein thrombus was evident likely owing to a local or systemic hypercoagulable state.

Comments

Full coagulation panel with d dimers and SDP are recommended. Given the thrombocytopenia, evaluation for tick-bourne disease would also be indicated. This case was lost to follow-up.

Clinical Differential Diagnosis

Primary liver disease – acute, chronic, metabolic, or neoplastic; Hypertriglyceridemia – recent meal, uncontrolled hypothyroidism; Hematuria – bacterial cystitis, neoplasia, renal disease; Thrombocytopenia – lab error, infectious, neoplastic, immune mediated.

Sampling

None taken.

Patient Information

Patient Name : Abby E
Gender : Female, Spayed
Species : Canine
Type of Imaging : Ultrasound
Status : Complete
Liz Wuz Here : Yes
Code : 08_00035

Clinical Signs

  • Weakness

History

  • Hypothyroidism

Exam Finding

  • Arrhythmia
  • Tachypnea

Images

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Blood Chemistry

  • Alkaline Phosphatase (SAP), High
  • AST (SGOT), High
  • CPK, High
  • Hypertriglyceridemia

CBC

  • Basophils, High
  • Eosinophils, High
  • Lymphocytes, Low

Clinical Signs

  • Weakness

Urinalysi

  • Blood Present
  • Epithelial Cells Present
  • Protein Present
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