Skip to content
Customize Consent Preferences

We use cookies to help you navigate efficiently and perform certain functions. You will find detailed information about all cookies under each consent category below.

The cookies that are categorized as "Necessary" are stored on your browser as they are essential for enabling the basic functionalities of the site. ... 

Always Active

Necessary cookies are required to enable the basic features of this site, such as providing secure log-in or adjusting your consent preferences. These cookies do not store any personally identifiable data.

No cookies to display.

Functional cookies help perform certain functionalities like sharing the content of the website on social media platforms, collecting feedback, and other third-party features.

No cookies to display.

Analytical cookies are used to understand how visitors interact with the website. These cookies help provide information on metrics such as the number of visitors, bounce rate, traffic source, etc.

No cookies to display.

Performance cookies are used to understand and analyze the key performance indexes of the website which helps in delivering a better user experience for the visitors.

No cookies to display.

Advertisement cookies are used to provide visitors with customized advertisements based on the pages you visited previously and to analyze the effectiveness of the ad campaigns.

No cookies to display.

Pancreatic carcinoma and splenic metastasis in a 15 year old FS DSH cat

Case Study

Pancreatic carcinoma and splenic metastasis in a 15 year old FS DSH cat

A 15-year-old FS DSH cat was presented for weight loss, decreased appetite, hematuria, and lethargy. Abnormalities on physical examination included a large irregular mass in the mid-abdomen and left-sided iridial neovascularization with a small white mass on ventral/lateral limbus. On CBC, anemia and lymphopenia were present. Blood chemistry showed mild hypoglycemia, elevated BUN, and elevated AST activity. Patient had a low T4.

A 15-year-old FS DSH cat was presented for weight loss, decreased appetite, hematuria, and lethargy. Abnormalities on physical examination included a large irregular mass in the mid-abdomen and left-sided iridial neovascularization with a small white mass on ventral/lateral limbus. On CBC, anemia and lymphopenia were present. Blood chemistry showed mild hypoglycemia, elevated BUN, and elevated AST activity. Patient had a low T4. Survey radiographs showed mild tracheal elevation in the cranial mediastinum, no obvious pulmonary metastasis, normal heart size, and a mass effect in the mid abdomen.

Sonographic Differential Diagnosis

Multicentric neoplasia, likely lymphosarcoma or similar neoplastic process.

Image Interpretation

The abdomen in this patient presented multiple hypoechoic lymph node masses involving the spleen, pancreas, and periportal lymph nodes. A mild amount of abdominal fluid was noted. Multiple hypoechoic nodular changes are noted in the area of the left pancreatic limb consistent with lymph nodes or pancreatic nodules. A large hypoechoic pancreatic mass is present. The spleen in the near field is significantly irregular with multiple hypoechoic nodular changes and scalloping capsular contour. The mid field demonstrates an adjacent infiltrated lymph node.

DX

Pancreatic carcinoma with splenic metastasis

Outcome

A guarded prognosis was given. The patient was treated with steroids and gastroprotectants.

Clinical Differential Diagnosis

Abdominal neoplasia of renal, pancreas, intestine, spleen, or mesenteric origin, lymphoma, abdominal cyst, hydronephrosis.

Sampling

US-guided FNA cytology from pancreas and spleen revealed pancreatic carcinoma and splenic congestion with metastatic tumor cells, respectively.

Patient Information

Patient Name : Maude N
Gender : Female, Spayed
Species : Feline
Type of Imaging : Ultrasound
Book : yes
Status : Complete
Liz Wuz Here : Yes
Code : 05_00051

Clinical Signs

  • Anorexia
  • Hematuria
  • Lethargy
  • Weight loss

History

  • Decreased appetite
  • Hematuria
  • Lethargy
  • Weight Loss

Exam Finding

  • Ocular abnormality
  • Palpable mass

Images

05-00051_image_01_0515201102391205-00051_image_02_05152011024008

Blood Chemistry

  • AST (SGOT), High
  • BUN high
  • Glucose, Low
  • Hypothyroidism

CBC

  • Lymphocytes, Low
  • RBC, Low

Clinical Signs

  • Anorexia
  • Hematuria
  • Lethargy
  • Weight loss