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Multiple myeloma diagnosed by jejunal lymph node aspirate/cytology in a 8 year old DSH cat

Case Study

Multiple myeloma diagnosed by jejunal lymph node aspirate/cytology in a 8 year old DSH cat

An 8-year-old feline DSH was presented for evaluation of weight loss. Abnormalities on serum biochemistry were severe hyperglobulinemia (globulin 91,) elevated bilirubin and fPL. Chronic bronchitis was evident on survey radiographs.

An 8-year-old feline DSH was presented for evaluation of weight loss. Abnormalities on serum biochemistry were severe hyperglobulinemia (globulin 91,) elevated bilirubin and fPL. Chronic bronchitis was evident on survey radiographs.

Sonographic Differential Diagnosis

Multi centric, regional lymphadenopathy mesenteric root and infiltrative splenic pattern. There is a strong suspicion for multiple myeloma or lymphoma or similar neoplasia. Possible chronic infectious with reactive lymphadenitis. Hyperechoic surrounding fat. FNAs were performed of the spleen and lymph node.

Image Interpretation

The proximal colon was slightly thickened and measured 0.3 cm. Jejunal lymph node mass was noted in this patient and measured 3.5 cm. Caudal mesenteric lymph node was also mildly enlarged and slightly thickened with heterogenous parenchymal changes. The spleen was enlarged and micronodular measuring 1.13 cm. This is strongly suspicious for infiltrative disease. Rapid view of the heart revealed no evident pathology.

DX

Multiple myeloma

Outcome

None

Clinical Differential Diagnosis

Pancreas – chronic pancreatitis, neoplasia, abscess
GIT – IBD, neoplasia, granulomatous enteritis, foreign body
FIP, peritonitis
Lymphoma, multiple myeloma

Sampling

Jejunal lymph node mass FNA/cytology revealed multiple myeloma.

Patient Information

Patient Name : Rosie L
Species : Feline
Type of Imaging : Ultrasound
Status : Complete
Liz Wuz Here : Yes
Code : 04_00421

Clinical Signs

  • Weight loss

Images

rosie_leman_multiple_myeloma_feline_dec_colonrosie_leman_multiple_myeloma_feline_caudal_mesenteric_lnrosie_leman_multiple_myeloma_feline_jejunal_lnrosie_leman_multiple_myeloma_feline

Blood Chemistry

  • Globulin, High
  • Total Bilirubin, High

Clinical Signs

  • Weight loss

Special Testing

  • fPLI Positive