A 12-year-old FS DSH was presented for vomiting for several months, inappetence, and weight loss. On survey radiographs, a possible thickened stomach wall was identified.
A 12-year-old FS DSH was presented for vomiting for several months, inappetence, and weight loss. On survey radiographs, a possible thickened stomach wall was identified.
Case Study
Lymphoma, eosinophilic lymphadenitis, and eosinophilic enteritis in a 12 year old FS DSH cat
Sonographic Differential Diagnosis
Infiltrative intestinal neoplasia or inflammatory change is most likely. The lymph nodes may be enlarged due to neoplastic or inflammatory processes as well.
Image Interpretation
Thickened jejunal segment with increased muscularis layer but no loss of layering (image 1). Mild cranial mesenteric root lymphadenopathy (image 2). There is a loss of layering in some segments of the bowel (video 1).
DX
Lymphoma, eosinophilic lymphadenitis, and eosinophilic enteritis
Outcome
The patient was treated with chemotherapy, which resulted in a marked improvement. Recheck ultrasound two months after starting chemotherapy revealed that the mesenteric lymph nodes had enlarged. The prednisone was increased to 5mg BID and the chemotherapy protocol changed to single agent carmustine. On CBC two weeks later, neutrophilia, lymphopenia, and anemia were evident. Mild hypercholesterolemia was present on serum biochemistry. The abdominal mass felt smaller on palpation. Three months after starting chemotherapy, the patient showed loss of appetite, weakness, and labored respiration. The owner elected euthanasia.
Clinical Differential Diagnosis
GI tract disease (neoplasia, partial obstruction, IBD, foreign body, dietary hypersensitivity), pancreatic disease (chronic pancreatitis, neoplasia), liver disease, renal disease.
Sampling
Histopathology of full thickness surgical biopsy samples revealed lymphoma, eosinophilic lymphadenitis, and eosinophilic enteritis.
Video
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Patient Information
Patient Name :
Cynder G
Gender :
Female, Spayed
Species :
Feline
Type of Imaging : Ultrasound
Book :
yes
Status :
Complete
Liz Wuz Here :
Yes
Code :
04_00181
Clinical Signs
- Anorexia
- Vomiting
- Weight loss
History
- Anorexia
- Decreased appetite
- Vomiting
- Weight Loss
Images
Clinical Signs
- Anorexia
- Vomiting
- Weight loss