Case Study

Histiocytic Sarcoma in a 10 year old FS Golden Retriever dog

A 10-year-old FS Golden retriever was presented for evaluation of lethargy and progressive anorexia. Isosthenuria was present on urinalysis. Abnormalities on CBC and serum biochemistry were thrombocytopenia, regenerative anemia, and hypoglobulinemia. Survey thoracic radiographs showed pulmonary nodules.

A 10-year-old FS Golden retriever was presented for evaluation of lethargy and progressive anorexia. Isosthenuria was present on urinalysis. Abnormalities on CBC and serum biochemistry were thrombocytopenia, regenerative anemia, and hypoglobulinemia. Survey thoracic radiographs showed pulmonary nodules.

DX

Histiocytic sarcoma.

Sonographic Differential Diagnosis

R/O metastatic neoplasia likely sarcoma or similar metastatic process. Metastatic carcinoma is also a possibility and a minor possibility of suppurative embolic disease.

Image Interpretation

The liver presented multiple target type lesions with hyperechoic center and hypoechoic surrounding rim. There was dysruption of internal architecture. The gallbladder presented thin walls with normal, primarily anechoic content. The cystic and common bile ducts were normal. No periportal lymphadenopathy was evident. No overt structural evidence of inflammatory, infiltrative or regenerative pathology was noted.