Hepatocutaneous Syndrome in a 9 year old MN Beagle

Case Study

Hepatocutaneous Syndrome in a 9 year old MN Beagle

Beagle, NM, 9 years. Progressive foot pad hyperkeratosis, general malaise, increased itching, increased liver enzymes, suspect hepatocutaneous syndrome PE: marked foot pad hyperkeratosis with surrounding erosions, perioral crusting and erosive dermatitis, perianal crusting Medications: MiconaHex+Triz shampoo Albumin 2.6, ALT 365, ALKP 375m white count 16000.

Beagle, NM, 9 years. Progressive foot pad hyperkeratosis, general malaise, increased itching, increased liver enzymes, suspect hepatocutaneous syndrome PE: marked foot pad hyperkeratosis with surrounding erosions, perioral crusting and erosive dermatitis, perianal crusting Medications: MiconaHex+Triz shampoo Albumin 2.6, ALT 365, ALKP 375m white count 16000.

DX

Suspect hepatocutaneous syndrome.

Sonographic Differential Diagnosis

Diffuse nodular liver.

Image Interpretation

The liver presented heterogenous parenchymal changes and increased portal markings as well as isoechoic, expansive nodules. Given the hyperkeratosis There is a strong potential for hepatocutaneous syndrome. Bile acid profile and core liver biopsy is recommended.

Outcome

Liver biopsy and bile acid profile would be warranted.

Sampling

Liver biopsy would be warranted.

Patient Information

Gender : Male, Neutered
Species : Canine
Type of Imaging : Ultrasound
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