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Gall bladder mucocele, cholangiohepatitis in a 6 year old MN Cocker Spaniel dog

Case Study

Gall bladder mucocele, cholangiohepatitis in a 6 year old MN Cocker Spaniel dog

A 6-year-old MN Cocker Spaniel dog with history of anxiety was presented for one episode of vomiting, anorexia, decreased drinking, lethargy, tachypnea, and restless behavior. Physical exam found patient painful in the mid-abdomen. Blood chemistry revealed elevated total protein, hyperbilirubinemia, hypercholesterolemia, hyperglobulinemia, elevated Alkaline Phosphatase, elevated ALT, elevated AST and elevated GGTP. CBC found leukocytosis consisting of neutrophilia, high bands and monocytosis, and thrombocytopenia. Patient was admitted for I.V. fluid therapy and supportive care.

A 6-year-old MN Cocker Spaniel dog with history of anxiety was presented for one episode of vomiting, anorexia, decreased drinking, lethargy, tachypnea, and restless behavior. Physical exam found patient painful in the mid-abdomen. Blood chemistry revealed elevated total protein, hyperbilirubinemia, hypercholesterolemia, hyperglobulinemia, elevated Alkaline Phosphatase, elevated ALT, elevated AST and elevated GGTP. CBC found leukocytosis consisting of neutrophilia, high bands and monocytosis, and thrombocytopenia. Patient was admitted for I.V. fluid therapy and supportive care.

Sonographic Differential Diagnosis

Inflamed gall bladder mucocele and inflammatory hepatopathy. Minor potential for infiltrative hepatic disease.

Image Interpretation

The gall bladder is moderately distended with suspended stellate debris. The tissue near the neck of the gall bladder is hyperechoic and ill-defined suggestive for inflammation. In my experience, this is the most frequent area of inflammation associated with mucoceles and prospective site of rupture. Hepatic parenchyma has a coarse architecture and increased portal markings suggestive for fibrosis, remodeling and chronic inflammatory disease.

DX

Gall bladder mucocele, cholangiohepatitis

Outcome

Immediate emergency exploratory surgery was strongly recommended, with the possibility of cholecystectomy, anaerobic and aerobic cultures, and liver/gallbladder biopsy. Surgery was not performed; patient was discharged to the owner and never pursued further treatments. The patient was lost follow-up.

Comments

No video is available for this patient.

Clinical Differential Diagnosis

Liver pathology: hepatitis- infectious, chronic active, hepatopathy-toxic, biliary mucocele, extrahepatic bile duct obstruction, cholecystitis; Pancreatic pathology: pancreatitis, suspected infection (hepatic or pancreatic abscess); GI pathology: gastroenteritis; possible initial stages of DIC with platelet consumption

Sampling

None taken

Patient Information

Patient Name : Jordan D
Gender : Male, Neutered
Species : Canine
Type of Imaging : Ultrasound
Status : Complete
Liz Wuz Here : Yes
Code : 03_00105

Clinical Signs

  • Anorexia
  • Lethargy
  • Vomiting

History

  • Anxiety

Exam Finding

  • Abdominal Pain

Images

Jordan_d_mucicele_1_1209200905570403_00105_Jordand_cbd2_07152011023217

Blood Chemistry

  • Alkaline Phosphatase (SAP), High
  • ALT (SGPT), High
  • AST (SGOT), High
  • Cholesterol, High
  • GGT High
  • Globulin, High
  • Total Bilirubin, High
  • Total Protein, High

CBC

  • Bands
  • Monocytes, High
  • Neutrophils, High
  • Platelet Count, Low

Clinical Signs

  • Anorexia
  • Lethargy
  • Vomiting