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CT Right-Sided Cerebral Intraaxial Neoplasia in a 6 year old MN Giant Schnauzer dog

Case Study

CT Right-Sided Cerebral Intraaxial Neoplasia in a 6 year old MN Giant Schnauzer dog

This 6 year old MN Giant Schnauzer has a history of seizures. Right eye enucleation with mass 4 weeks ago.  Presented for seizure activity.

This 6 year old MN Giant Schnauzer has a history of seizures. Right eye enucleation with mass 4 weeks ago.  Presented for seizure activity.

Image Interpretation

CT of the head, plain and iodinated post contrast: the scan showed a status after enucleation of the right globe and implantation of an intrascleral prosthesis. There was a moderate right-sided enophthalmus due to extraocular muscle atrophy noted. There was mild well delineated uniformly enhancing granulation tissue formation seen as expected after enucleation surgery. The sole intracranial abnormality noted in the post contrast bone window is midline deviation of the cerebral falx to the left in the forebrain, level with the frontal, parietal and temporal lobes, indicative of a mass effect within the right cerebral hemisphere. Only after manual window adjustment, the post contrast series showed a space occupying lesion associated with the right cerebral hemisphere which showed mild non-uniform contrast enhancement, emphasized in the periphery of the lesion and sparing parts of the lesion center. The size of the space occupying lesion was approximately 2.5 x 2.5 x 2cm. There appeared to be contact between the ventricular system and the lesion. Secondary lateral ventricular asymmetry was present. The iris of the left globe showed irregular thickness with nodular changes which were mainly protruding into posterior direction. There was minor right-sided submandibular and medial retropharyngeal lymph node enlargement with preserved short-to-long axis ratio and contrast uptake pattern noted.

DX

The CT findings are compatible with a right-sided cerebral neoplasia, most likely intraaxial in origin. Differential diagnoses mainly include glial cell neoplasms such as oligodendroglioma or astrocytoma. Oligodendroglioma appears more likely here because the lesion seems to have contact with the ventricular system. Round cell neoplasms such as lymphoma or histiocytic sarcoma are possible differentials.

Outcome

There was reactive hyperplasia of the submandibular and medial retropharyngeal lymph node likely unrelated to the brain lesion but as sequel to the enucleation surgery. The changes of the left iris may indicate iris cysts or neoplasia such as melanoma versus uveitis and should be checked in an ophthalmologic examination or with ultrasound.

Patient Information

Patient Name : Dillon Cowan - Neel VH
Gender : Male, Neutered
Species : Canine
Type of Imaging : Ultrasound

Clinical Signs

  • Seizures

History

  • Seizures

Exam Finding

  • Ocular abnormality

Images

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Clinical Signs

  • Seizures