CT and CYT – Nasal lymphoma with aggressive osteolysis and upper respiratory tract obstruction in a 7 year old MN Australian Shepherd

Case Study

CT and CYT – Nasal lymphoma with aggressive osteolysis and upper respiratory tract obstruction in a 7 year old MN Australian Shepherd

This 7 year old MN Australian Shepherd has a 2 week history of epistaxis when playing, nose seems congested.

Physical exam: unable to pass air in nasal passages, open mouth breathing

CBC/Chem: ALB, ALT, ALKP high; Glob, amylase low

This 7 year old MN Australian Shepherd has a 2 week history of epistaxis when playing, nose seems congested.

Physical exam: unable to pass air in nasal passages, open mouth breathing

CBC/Chem: ALB, ALT, ALKP high; Glob, amylase low

DX

The computed tomographic findings are compatible with a malignant nasal soft tissue neoplasia with secondary aggressive osteolysis and upper respiratory tract obstruction.

Sonographic Differential Diagnosis

FNA/cytology of nasal mass consistent with round cell neoplasia, lymphoma most likely

Image Interpretation

CT of the head, plain and post-contrast – The computed tomography of the head reveals a soft tissue attenuating mass lesion within the mid and caudal third of the right nasal cavity. The mass measures 6.5 x 3 x 2.5 cm and causes a complete obstruction of the right nasal passage including the ventral nasal meatus & nasal. The mass causes severe aggressive permeative osteolysis of the nasal, maxillary, palatinla and vomer bone and invades the left nasal cavity as well as the oral cavity. Extensive nasal turbinate destruction as well as destruction and deviation of the nasal septum is noted. The cribriform plate is intact. The right frontal sinus as well as the right nasal cavity caudal to the mass are filled with soft tissue attenuating, non-enhancing secretions. The rostral third of the right nasal cavity reveals accumulation of fluids, such as nasal secretions and/or hemorrhage on its floor.

Outcome

Likely differentials include adenocarcinoma, squamous cell carcinoma, lymphosarcoma, melanoma and fibrosarcoma. There is right-sided secondary secretory frontal sinusitis and rhinitis/hemorrhage.
Full tumor staging would require sampling of the lymph nodes as well as a 3 view radiographic study of the thorax and abdominal ultrasound next to the primary tumor biopsy.
Radiative therapy and/or chemotherapeutic treatment may be considered depending on the results.

Patient Information

Patient Name : Jubi Fratarcangeli/CVC
Gender : Male, Neutered
Species : Canine
Type of Imaging : Ultrasound
Status : Complete
Liz Wuz Here : Yes

Clinical Signs

  • Epistaxis
  • Nasal congestion
  • Open mouth breathing

Images

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Clinical Signs

  • Epistaxis
  • Nasal congestion
  • Open mouth breathing
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