Chronic active pancreatitis diagnosed by ultrasound-guided FNA in a 15 year old MN DSH cat

Case Study

Chronic active pancreatitis diagnosed by ultrasound-guided FNA in a 15 year old MN DSH cat

This 15-year-old neutered male DSH cat presented for vague not-doing-right clinical signs. Dysuria, anorexia, and lethargy were described. The physical exam revealed a moderately painful mid-cranial abdomen and mild pyrexia. The first CBC was normal except for mild increased bands. The initial blood chemistry analysis revealed only slight azotemia which normalized during hospitalization. Repeat analysis, after 5 days of hospitalization and supportive intravenous care, revealed a mild leukocytosis with moderately increased bands and slight anemia with anisocytosis.

This 15-year-old neutered male DSH cat presented for vague not-doing-right clinical signs. Dysuria, anorexia, and lethargy were described. The physical exam revealed a moderately painful mid-cranial abdomen and mild pyrexia. The first CBC was normal except for mild increased bands. The initial blood chemistry analysis revealed only slight azotemia which normalized during hospitalization. Repeat analysis, after 5 days of hospitalization and supportive intravenous care, revealed a mild leukocytosis with moderately increased bands and slight anemia with anisocytosis. Moderately increased fPLI was also present.

DX

Chronic active pancreatitis

Sonographic Differential Diagnosis

Chronic active pancreatitis with remodeling and likely sectoral avascular necrosis. Carcinoma is possible.

Image Interpretation

A mixed hypoechoic and variably echogenic mass of tissue is present in the pancreatic region. Minimal color flow signals were present (not shown).

Outcome

The patient responded initially to IV fluid support, antibiotics, and pain management over a 9 day period. Surgical removal of the pancreatic sequestrum and biopsy was recommended but declined by the owner. The patient was humanely euthanized due to poor response to therapy and progressive deterioration. We cannot eliminate the possibility of an underlying infectious agent such as Toxoplasmosis and/or Bartonella playing a role in this case. In addition, even though the cytology and PLI were suggestive for a chronic pancreatitis, underlying neoplasia such as pancreatic carcinoma remains a concern.

Comments

No video available on this patient.

Clinical Differential Diagnosis

Pancreatitis, infectious disease, abscess, neoplasia, IBD.

Sampling

22-gauge US-guided FNA of the lesion revealed chronic active pancreatitis.

Patient Information

Patient Name : May B
Gender : Male, Neutered
Species : Feline
Type of Imaging : Ultrasound
Status : Complete
Liz Wuz Here : Yes
Code : 05_00032

Clinical Signs

  • "Not Doing Right"
  • Anorexia
  • Dysuria
  • Lethargy

Exam Finding

  • Abdominal Pain
  • Fever

Images

May1_11262009102142May_2_11262009102210

Blood Chemistry

  • BUN high
  • Creatinine, High

CBC

  • Anisocytosis
  • Bands
  • WBC, High

Clinical Signs

  • "Not Doing Right"
  • Anorexia
  • Dysuria
  • Lethargy

Special Testing

  • fPLI Positive
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