Chronic active pancreatitis in a 17 year old FS DSH cat

Case Study

Chronic active pancreatitis in a 17 year old FS DSH cat

This 17-year-old FS DSH was presented for anorexia, lethargy, vocalization and mild weight loss. The physical exam revealed a painful cranial abdomen and poor body condition. The CBC and blood chemistry demonstrated mildly elevated BUN, mildly elevated creatinine, mildly elevated ALT, mildly elevated SAP, mildly elevated total bilirubin and mildly elevated CPK with mild anemia and moderate leukocytosis with a left shift. Urinalysis was normal with a urine specific gravity of 1.036.

This 17-year-old FS DSH was presented for anorexia, lethargy, vocalization and mild weight loss. The physical exam revealed a painful cranial abdomen and poor body condition. The CBC and blood chemistry demonstrated mildly elevated BUN, mildly elevated creatinine, mildly elevated ALT, mildly elevated SAP, mildly elevated total bilirubin and mildly elevated CPK with mild anemia and moderate leukocytosis with a left shift. Urinalysis was normal with a urine specific gravity of 1.036.

DX

Chronic active pancreatitis

Sonographic Differential Diagnosis

Suspect mild to moderate, acute exacerbation of chronic pancreatitis with mild peripancreatic inflammation. Mild, diffuse common bile duct dilation. Common bile duct dilation in an older feline patient could be multifactorial with potential causes including referred inflammation with atony secondary to pancreatitis, primary cholangitis, residual dilation secondary to a prior inflammatory process or a combination thereof.

Image Interpretation

Mild to moderate generalized pancreatic enlargement is present. The pancreatic serosal margins are mildly undulating and the parenchyma is heteroechoic, suggesting fibrosis with serosal contracture. The pancreatic duct is also dilated and tortuous. The peripancreatic omentum and mesentery are mildly echogenic. In the second video, a dilated and tortuous common bile duct is visible between the descending duodenum and proximal aspect of the right limb of the pancreas. The common bile duct is likely dilated at the level of the duodenal papilla.

Outcome

The patient was treated in hospital for pancreatitis and was discharged successfully.

Clinical Differential Diagnosis

Pancreatitis, cholangitis, neoplasia, peritonitis, IBD, gastrointestinal obstruction.

Sampling

US guided FNA revealed mixed pancreatic inflammation, pancreatitis.

UA Specific Gravity Range

1.036

Patient Information

Patient Name : Mistymarie G
Gender : Female, Spayed
Species : Feline
Type of Imaging : Ultrasound
Status : Complete
Liz Wuz Here : Yes
Code : 05_00010

Clinical Signs

  • Anorexia
  • Lethargy
  • Vocalizing
  • Weight loss

History

  • Anorexia
  • Lethargy
  • Weight Loss

Exam Finding

  • Abdominal Pain
  • Weight loss

Images

Mistymarie_1_11232009055438Mistymarie_2_11232009055456

Blood Chemistry

  • Alkaline Phosphatase (SAP), High
  • ALT (SGPT), High
  • BUN high
  • CPK, High
  • Creatinine, High
  • Total Bilirubin, High

CBC

  • Left Shift
  • RBC, Low
  • WBC, High

Clinical Signs

  • Anorexia
  • Lethargy
  • Vocalizing
  • Weight loss
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