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09-00027 Princess S Pyometra BK—-NEEDS C—-NO IMAGES—-

Case Study

09-00027 Princess S Pyometra BK—-NEEDS C—-NO IMAGES—-

An 8-year-old F Miniature Schnauzer with diabetes was presented for polyuria/polydipsia, intermittent vomiting, and vaginal discharge. The only abnormality on physical examination was pyrexia. Urine had a cloudy and yellow appearance, which on analysis showed normal specific gravity, 3+ proteinuria, 3+ glucosuria, 2+ ketones, 3+ hematuria, and bacilli. The patient was treated with a course of antibiotics as the owner declined further workup. The following day the patient was returned as she was vomiting bile. An audible murmur was present on physical exam.

An 8-year-old F Miniature Schnauzer with diabetes was presented for polyuria/polydipsia, intermittent vomiting, and vaginal discharge. The only abnormality on physical examination was pyrexia. Urine had a cloudy and yellow appearance, which on analysis showed normal specific gravity, 3+ proteinuria, 3+ glucosuria, 2+ ketones, 3+ hematuria, and bacilli. The patient was treated with a course of antibiotics as the owner declined further workup. The following day the patient was returned as she was vomiting bile. An audible murmur was present on physical exam. CBC showed anemia, leukocytosis, thrombocytopenia, neutrophilia, monocytosis, and basophilia. On blood chemistry hyperglycemia, mild hypoalbuminemia, elevated ALP activity, hypercholesterolemia, mild hypocalcemia, low chloride, and hypoamylasemia were present.

Sonographic Differential Diagnosis

Pyometra with tissue thickening.

Image Interpretation

The caudal abdomen presented a fluid filled uterus with a 2cm tissue thickening at the base of the uterus mostly likely of inflammatory nature, however early neoplasia cannot be entirely ruled out. The ovaries presented a minor cyst change yet were otherwise normal.

Outcome

The patient was treated with IV fluids, hetastarch, and B-vitamins. An ovariohysterectomy was performed. Recovery was uneventful and she was treated with antibiotics and NSAIDS. At sutures out appointment, she was doing well and the blood glucose had normalized.

Clinical Differential Diagnosis

Diabetic ketoacidosis Pyometra Secondary peritonitis – rupture uterus/urinary bladder UTI with secondary septicemia Infectious disease – Ehrlichiosis/Leishmaniasis

Sampling

None taken. (Biopsy of the uterine base was suggested but not sampled).

Patient Information

Gender : Female, Intact
Species : Canine
Type of Imaging : Ultrasound

Clinical Signs

  • PU-PD
  • Vomiting

History

  • Diabetes, controlled

Exam Finding

  • Fever
  • Heart Murmur

Images

princesssangiardipyometraemerson1_11012012042249

Blood Chemistry

  • Albumin, Low
  • Alkaline Phosphatase (SAP), High
  • Calcium, Low
  • Chloride, Low
  • Cholesterol, High
  • Glucose, High

CBC

  • Basophils, High
  • Monocytes, High
  • Neutrophils, High
  • Platelet Count, Low
  • RBC, Low
  • WBC, High

Clinical Signs

  • PU-PD
  • Vomiting

Urinalysi

  • Appearance Turbid
  • Bacteria Present
  • Blood Present
  • Glucose Present
  • Ketones Present
  • Protein Present