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Leptospirosis in a 13-year-old MN Border Collie: Our Case Of The Month September 2014

Case Of the Month

Leptospirosis in a 13-year-old MN Border Collie: Our Case Of The Month September 2014

A 13-year-old MN Border Collie was presented for anorexia. Blood chemistry revealed moderate to severe BUN, creatinine and phosphorus with minor ALT, CPK and globulin elevations. Urinalysis revealed isosthenuria was present with a urine PH of 6.0 and some epithelial cells. Clinical dehydration and depression was present. Survey abdominal radiographs and CBC were unreremarkable.

A 13-year-old MN Border Collie was presented for anorexia. Blood chemistry revealed moderate to severe BUN, creatinine and phosphorus with minor ALT, CPK and globulin elevations. Urinalysis revealed isosthenuria was present with a urine PH of 6.0 and some epithelial cells. Clinical dehydration and depression was present. Survey abdominal radiographs and CBC were unreremarkable.

DX

Acute nephritis presentation with pericapsular fluid accumulation. Immature gallbladder mucocele. Suspect Leptospirosis or acute renal toxin.

Outcome

The patient tested strong positive for Leptospirosis and responded to medical therapy. See the happy patient sporting his handsome e-collar and doing well!

Comments

 
 

Treatment for renal failure is recommended. Blood pressure, GI protectants, and IV Ampicillin is warranted given the strong potential for Leptospirosis. Plasma transfusion with plasma expanders would be ideal. Urine culture and sensitivity is warranted. Assessment for toxin exposure would also be recommended such as Aflatoxin or plant ingestion.  Core renal biopsy may be necessary. Dialysis would be ideal if refractive to therapy.

Note: The pericapsular renal fluid accumulation is a frequent sonographic finding in cases of Leptospirosis that we see in the northeast United States, the elevated renal _/- liver enzymes wiht depression and relkatively minor sturctural renal changes wiht pericapsular fluid accumulation is a personal red flag for leptospirosis. Of course other acute renal insults can do this but since the northeast uinited states is endemic for leptsopirosis we must consider it on the forefront, especially in the days following heavy rain in the region.

 

Clinical Differential Diagnosis

Acute kidney injury – toxic, infectious (Leptospira, bacterial nephritis, septicemia), hypoxia, renolith, ureteral obstruction, lymphoma.)
ALT elevation: inflammatory or reactive hepatopathy

UA PH

6.0

UA PH

6.0

Sampling

Lepto Titer strong positive.

Sonographic Differential Diagnosis

Acute nephritis presentation with pericapsular fluid accumulation. Immature gallbladder mucocele. Suspect Leptospirosis or acute renal toxin.

Image Interpretation

The right kidney presented cortical infarct at the caudal pole. The right kidney measured 7.06 cm.
The left kidney measured 6.97 cm. Pericapsular fluid pattern was noted around both kidneys (more evident on left caudal pole) with
disruption of the corticomedullary definition. Slight pyelectasia was noted in the left kidney as well.
Ill defined pericapsular fat was noted primarily around the left kidney indicative of inflammation. . The gallbladder presented suspended debris and double layered wall. The cystic duct was dilated as was the common bile duct at 0.36 cm. This is consistent with immature mucocele. The liver presented a mild increase in the portal markings.

UA Specific Gravity Range

1010

Video

Patient Information

Patient Name : Bailey Z
Gender : Male, Neutered
Species : Canine
Book : yes

Clinical Signs

  • Anorexia
  • Depression

History

  • Anorexia

Exam Finding

  • Weakness

Images

lepto_jpeg_1_bailey_ziemba_-1lepto_2_rk_bailey_ziemba_rossmoyne_gb_patient

Blood Chemistry

  • BUN high
  • BUN/Creatinine Ratio, High
  • Creatinine, High
  • Elevated Liver Enzymes
  • Globulin, High

Clinical Signs

  • Anorexia
  • Depression

Special Testing

  • Leptospirosis Positive

Urinalysi

  • Epithelial Cells Present
  • pH Low
  • Specific Gravity High
  • Specific Gravity Low