A 7-year-old SF mixed breed dog was presented for evaluation of PU/PD and polypnea. On physical examination the fur on the flanks was bilaterally thin and she had a pot-bellied appearance. Urinalysis showed SG of 1.023 and 2+ protein. Abnormalities on serum biochemistry were mildly elevated ALT activity (150 U/l). Low-dose dexamethasone suppression showed cortisol of: pre 5.8, 4 hour 5.4; and 8 hour 4.8 mg/dl.