A 13-year-old spayed female Pit Bull Terrier mix dog with history of confirmed transitional cell carcinoma of the cystourethral junction presented for a lack of improvement in clinical signs after antibiotics. The dog had previously been diagnosed with hypothyroidism. Past urinalysis revealed hyposthenuria, hematuria, and pyuria. Recheck urinalysis results were similar to previous results despite antibiotics. The patient was treated with Deramaxx. Several months later, the patient presented for follow-up diagnostics. Urinalysis showed ongoing hematuria and pyuria.

A 13-year-old spayed female Pit Bull Terrier mix dog with history of confirmed transitional cell carcinoma of the cystourethral junction presented for a lack of improvement in clinical signs after antibiotics. The dog had previously been diagnosed with hypothyroidism. Past urinalysis revealed hyposthenuria, hematuria, and pyuria. Recheck urinalysis results were similar to previous results despite antibiotics. The patient was treated with Deramaxx. Several months later, the patient presented for follow-up diagnostics. Urinalysis showed ongoing hematuria and pyuria. CBC was within normal limits, whereas blood chemistry revealed mildly elevated BUN, normal creatinine, and hypercholesterolemia. The patient was treated with Clavamox and famotidine. On recheck urinalysis one month later, 3+ proteinuria, 3+ hematuria, and leukocyturia were still evident.